Ophthalmic laser system integrated with speckle variance optical coherence tomography for real-time temperature monitoring

Lee, Mi Kyung; Lee, Chang-Ho; Cheon, Gyeongwoo; Kim, Jongmin; Jo, Dongki; Lee, Jihoon; Kang, Jin U.

doi:10.1117/12.2291183

Cited by 2 publications

(2 citation statements)

References 3 publications

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“…Laser-based treatments are frequently employed in ophthalmology for various retinal diseases [57,71]. Among the therapies that are currently in practice, selective retina therapy (SRT) is one of the most effective treatment methods [72].…”

Section: Sv-oct In Therapeutic Assessments Of Various Medical Treatmentsmentioning

confidence: 99%

Growing Trend to Adopt Speckle Variance Optical Coherence Tomography for Biological Tissue Assessments in Pre-Clinical Applications

Wijesinghe,

Kahatapitiya,

Lee

et al. 2024

Micromachines

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Speckle patterns are a generic feature in coherent imaging techniques like optical coherence tomography (OCT). Although speckles are granular like noise texture, which degrades the image, they carry information that can be benefited by processing and thereby furnishing crucial information of sample structures, which can serve to provide significant important structural details of samples in in vivo longitudinal pre-clinical monitoring and assessments. Since the motions of tissue molecules are indicated through speckle patterns, speckle variance OCT (SV-OCT) can be well-utilized for quantitative assessments of speckle variance (SV) in biological tissues. SV-OCT has been acknowledged as a promising method for mapping microvasculature in transverse-directional blood vessels with high resolution in micrometers in both the transverse and depth directions. The fundamental scope of this article reviews the state-of-the-art and clinical benefits of SV-OCT to assess biological tissues for pre-clinical applications. In particular, focus on precise quantifications of in vivo vascular response, therapy assessments, and real-time temporal vascular effects of SV-OCT are primarily emphasized. Finally, SV-OCT-incorporating pre-clinical techniques with high potential are presented for future biomedical applications.

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Section: Sv-oct In Therapeutic Assessments Of Various Medical Treatmentsmentioning

confidence: 99%

Growing Trend to Adopt Speckle Variance Optical Coherence Tomography for Biological Tissue Assessments in Pre-Clinical Applications

Wijesinghe,

Kahatapitiya,

Lee

et al. 2024

Micromachines

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show abstract

“…Using a similar idea, Lee et al [24] were able to monitor protein denaturation and coagulation process with svOCT, which was based on the speckle pattern change due to tissue temperature change. Also, Lee et al [25] used an in-house built svOCT system integrated into a commercial ophthalmic laser system and analyzed the relationship between the average laser energy and peak intensity of the svOCT image during selective retina therapy. But both papers didn't reveale the direct relationship between speckle variance values and temperature and cannot perform high-speed temperature assessment.…”

Section: Introductionmentioning

confidence: 99%

Intraoperative Speckle Variance Optical Coherence Tomography for Tissue Temperature Monitoring During Cutaneous Laser Therapy

Guo

Wei

Lee

et al. 2019

IEEE J. Transl. Eng. Health Med.

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Ophthalmic laser system integrated with speckle variance optical coherence tomography for real-time temperature monitoring

Cited by 2 publications

References 3 publications

Growing Trend to Adopt Speckle Variance Optical Coherence Tomography for Biological Tissue Assessments in Pre-Clinical Applications

Growing Trend to Adopt Speckle Variance Optical Coherence Tomography for Biological Tissue Assessments in Pre-Clinical Applications

Intraoperative Speckle Variance Optical Coherence Tomography for Tissue Temperature Monitoring During Cutaneous Laser Therapy

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