Ophthalmoplegia in an adult with chronic inflammatory demyelinating polyradiculoneuropathy

Abstract

The authors present a 75-year-old patient with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and ophthalmoplegia. The patient had recurrent exacerbations and remissions of her polyneuropathy over the course of one year. Antibodies to ganglioside GM-I were not detected. Ophthalmoplegia in CIDP is uncommon, but is reported to occur in 3-8% of patients. Ophthalmologists should be aware of the association of CIDP and ophthalmoplegia.

Neuro-ophthalmological Complications of Chronic Inflammatory Demyelinating Polyradiculoneuropathy

“…The best treatment for neuro-ophthalmological complications of CIDP is to treat the underlying condition with appropriate immunosuppression, with reports of resolution of papilloedema, 36 diplopia, 51,52 and optic neuritis, 33 although proptosis tends to persist despite treatment. 22 Other treatment options for refractory papilloedema include acetazolamide, optic nerve sheath fenestration, and CSF diversion surgery.…”