“…ker- Woudenberg and Roerdink, 1986;Bakker-Woudenberg et al, 1993Lopez-Berestein, 1987; Since the rise i n the number Of newer azole antifungal compounds have been synthesized and evaluated in vivo, alone [Clemons et al, 1995;Como and Dismukes, 1994;Dismukes, 1988;Fromtling, 1988;Georgiev, 1993;Hay, 1994;Kauffman, 1994;Peng and Galgiani, 19931 or associated with liposomes [Brasseur et al, 1991;Le Conte et al, 1991;Singh et al, 19931 or cyclodextrins [Hostetler et al, 1992;Van Doorne et al, 19881. Particular interest has been focused on the new triazole derivative itraconazole ( Fig.…”