2022
DOI: 10.3390/biomedicines10123232
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Opportunities and Challenges of Human IPSC Technology in Kidney Disease Research

Abstract: Human induced pluripotent stem cells (iPSCs), since their discovery in 2007, open a broad array of opportunities for research and potential therapeutic uses. The substantial progress in iPSC reprogramming, maintenance, differentiation, and characterization technologies since then has supported their applications from disease modeling and preclinical experimental platforms to the initiation of cell therapies. In this review, we started with a background introduction about stem cells and the discovery of iPSCs, … Show more

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