Optic Disc Edema From Papilledema

Zhang, Jason; Foroozan, Rod

doi:10.1097/iio.0000000000000006

Cited by 13 publications

(9 citation statements)

References 62 publications

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“…Pseudodrusen are accumulations of extruded axoplasm due to chronic papilloedema and by definition are absent with resolved papilloedema. [31][32][33][34][35] Pseudodrusen, although non-calcified, are similar to drusen, and both may be associated with obstructed axonal transport and accumulations of axoplasm. 7 It is possible that pseudodrusen and ODD represent a spectrum of optic nerve disorder resulting from axoplasmic flow stasis.…”

Section: Discussionmentioning

confidence: 99%

Increased Prevalence of Optic Disc Drusen after Papilloedema from Idiopathic Intracranial Hypertension: On the Possible Formation of Optic Disc Drusen

Birnbaum

Johnson

et al. 2016

Neuro-Ophthalmology

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This is a 25-year observational retrospective review of 372 consecutive participants with optic disc drusen or resolved papilloedema from idiopathic intracranial hypertension. The prevalence of optic disc drusen at 19% among eyes with resolved papilloedema was approximately 10 times higher and significantly increased (p < 0.001) as compared with the occurrence in the general population. Eyes with both resolved papilloedema and optic disc drusen had similar visual acuity and visual field outcome as compared with resolved papilloedema alone. Eyes with exposed drusen had significantly worse visual acuity and visual field outcome (p < 0.001) than buried drusen. The high prevalence of optic disc drusen after papilloedema has resolved suggests a non-coincidental relationship. Optic disc drusen formation can be a sequela of papilloedema.ARTICLE HISTORY

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Section: Discussionmentioning

confidence: 99%

Increased Prevalence of Optic Disc Drusen after Papilloedema from Idiopathic Intracranial Hypertension: On the Possible Formation of Optic Disc Drusen

Birnbaum

Johnson

et al. 2016

Neuro-Ophthalmology

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“…This condition is associated with several etiologies, including idiopathic intracranial 50 hypertension (IIH) 1-3 , sinus venous thrombosis 1, 2, 4, 5 , intracranial inflammation 1, 2 , 51 intracranial mass 6, 7 , and subarachnoid hemorrhage 1,2 . Papilledema has also been 52 documented in the Vision Impairment and Intracranial Pressure (VIIP) syndrome in 53 astronauts during and after prolonged space flight 8,9 .…”

mentioning

confidence: 99%

Relationship Between Optic Nerve Protrusion Measured by OCT and MRI and Papilledema Severity

Chang

Alperin

Bagci

et al. 2015

Invest. Ophthalmol. Vis. Sci.

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“…Papilledema must also be distinguished from pseudo-papilledema such as optic disc drusen. Since the root cause of papilledema is increased intracranial pressure (ICP) this is an alarming sign which may presage such entities as brain tumor, CNS inflammation, or idiopathic intracranial hypertension (IIH) [1].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Optic Nerve Head Changes in Patients with Papilledema Using Spectral-Domin Optical Coherence Tomography

Haleem

Hamed

Farid

et al. 2022

Benha Journal of Applied Sciences

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Background: Swelling of the optic disc caused by axoplasmic flow stasis in the optic nerve head as a consequence of elevated intracranial pressure is referred to as papilledema (PO) (ICP). Measurements of the ONH and retinal layers using optical coherence tomography (OCT) imaging are reliable and reproducible, including measurements of the average peripapillary retinal nerve fibre layer (RNFL) thickness, average total peripapillary retinal thickness (TRT), and comparisons for all OCT parameters reflecting swelling of the ONH or peripapillary retina. Papilledema (PO) has been shown to affect the optic nerve head (ONH), retinal nerve fibre layer (RNFL), peripapillary total retinal (PTR) thickness, and gaglion cell layer (GCL) by OCTA (OCT). 60 eyes were used in this investigation, which was a prospective casecontrol study. The patients were picked from Benha University Hospitals' outpatient ophthalmology clinic. Optic nerve group (A) consisted of 30 eyes from 30 healthy controls, 16 of whom had mild papilledema, and 14 of whom had moderate to severe papilledema, which was separated into two groups: Group B (16 patients) and Group C (14 patients). Patients with moderate to severe papilledema (C) had higher levels of ONHV than those with mild papilledema (B). Furthermore, the average ONHV in group (B) was higher than in group (A) (A). However, as compared to healthy people in group A, the CD ratio was lower in patients with papilledema in groups B and C. In group C, the average thickness of the RNFL was considerably larger in all quadrants than in group B.. In addition, group (B) had a thicker average RNFL than group (A). PTR thickness values in group (C) were considerably higher than those in group (A) in all quadrants (B). In addition, the average PTR thickness in group (B) was higher than that in group (A). The difference in GCL thickness between the two groups in our research was not statistically significant. The results of this research demonstrate that all of the OCT measures tested (CD/R, ONHV, PTR, RNFL) are useful in the diagnosis of PO. These metrics may also identify early papilledema, thus they can be used to track PO patients and see whether their condition improves or worsens as a result of therapy. When it comes to diagnosing and monitoring individuals with PO, the only criterion that has demonstrated no sensitivity is GCL.

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Optic Disc Edema From Papilledema

Cited by 13 publications

References 62 publications

Increased Prevalence of Optic Disc Drusen after Papilloedema from Idiopathic Intracranial Hypertension: On the Possible Formation of Optic Disc Drusen

Increased Prevalence of Optic Disc Drusen after Papilloedema from Idiopathic Intracranial Hypertension: On the Possible Formation of Optic Disc Drusen

Relationship Between Optic Nerve Protrusion Measured by OCT and MRI and Papilledema Severity

Assessment of Optic Nerve Head Changes in Patients with Papilledema Using Spectral-Domin Optical Coherence Tomography

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