Optic Nerve Hypoplasia With Good Visual Acuity

Superior segmental optic nerve hypoplasia in youth

“…Previous reports from Western countries 4,5,[7][8][9][10][11] have stated that SSOH is a sign of gestational diabetes. However, Japanese reports have not always supported this claim, 12,21 and neither did our study results.…”

Refractive laser surgery in children with coexisting medical and ocular pathology

“…Several authors describe successful results with amblyopia treatment for monocular structural anomalies. [15][16][17] Lengyel et al 18 describe 3 children with severe organic eye diseases in whom occlusion therapy resulted in achievement of relatively good visual acuity during the sensitive phase of visual plasticity. Conversely, Yang and Lambert 19 applied occlusion therapy in 5 children with a structural defect of the optic nerve or macula and did not find any evidence of visual improvement.…”

Optic nerve axons: life and death before birth

“…Vision and associated features: Severe hypoplasia causes blindness, but in lesser degrees a variety of abnormalities have been described, with some patients having clinically normal visual acuity [131][132][133] although field defects in those cases with good acuity are common. 133 Visual acuity is determined largely by the size of the papillomacular bundle, not with the overall size of the disc; there is not a very close correlation between the size of the optic disc and the visual function.…”