Optic Neuritis in an Adult Patient with Chickenpox

Azevedo, AR; Simões, Renata Toscano; Silva, F; Pina, S; Santos, Cristina; Pêgo, P; Teixeira, Sérgio Henrique

doi:10.1155/2012/371584

Cited by 6 publications

(4 citation statements)

References 7 publications

(14 reference statements)

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“…2 While direct viral invasion may play a role in rare parainfectious cases, the majority are believed to reflect postinfectious autoimmunity. There is no clear rule for the latency between viral infection and secondary ON, but in reviewing several cases in the literature, we found latencies of 2 days, 3 2 weeks, 4 and 4 weeks. 5 The range of latencies one could expect following COVID-19 infection could well be longer than with other infections, but as a rule, we felt that latencies of 3 months or longer put into question a true association, given the high frequency of COVID-19 infection in the population.…”

Section: Optic Neuritismentioning

confidence: 57%

Neuro-Ophthalmic Visual Impairment in the Setting of COVID-19

Dinkin

Sathi

2023

Semin Neurol

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We set out to describe in detail the afferent neuro-ophthalmological complications that have been reported in association with coronavirus disease 2019 (COVID-19) infection. We describe and elaborate on mechanisms of disease, including para-infectious inflammation, hypercoagulability, endothelial damage, and direct neurotropic viral invasion. Despite global vaccination programs, new variants of COVID-19 continue to pose an international threat, and patients with rare neuro-ophthalmic complications are likely to continue to present for care.Afferent complications from COVID-19 include homonymous visual field loss, with or without higher cortical visual syndromes, resulting from stroke, intracerebral hemorrhage, or posterior reversible leukoencephalopathy. Optic neuritis has frequently been reported, sometimes along with acute disseminated encephalomyelopathy, often in association with either myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) or less commonly aquaporin-4 seropositivity or in newly diagnosed multiple sclerosis. Ischemic optic neuropathy has rarely been reported. Papilledema, resulting either from venous sinus thrombosis or idiopathic intracranial hypertension in the setting of COVID-19, has also been described.Observed afferent neuro-ophthalmic associations need to be confirmed though larger comparative studies. Meanwhile, the range of possible complications should be recognized by neurologists and ophthalmologists alike, to facilitate faster diagnosis and treatment of both COVID-19 and its neuro-ophthalmic manifestations.

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Section: Optic Neuritismentioning

confidence: 57%

Neuro-Ophthalmic Visual Impairment in the Setting of COVID-19

Dinkin

Sathi

2023

Semin Neurol

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“…ARN generally involves immunocompetent patients, starts peripherally, and spreads centripetally ( 12 ). The clinical diagnosis of ARN is based on the diagnostic criteria established by the American Uveitis Society, which consists of: ( 1 ) one or more discrete foci of peripheral retinal necrosis, ( 2 ) occlusive retinal vasculitis with arteriolar involvement, ( 3 ) prominent inflammation in the anterior and posterior chambers, ( 4 ) circumferential disease spread, and ( 5 ) rapid progression of disease in the absence of treatment ( 13 ). ARN almost always occurs with reactivation of a herpetic latent virus, nonetheless, primary herpes infections may cause a clinical picture resembling ARN.…”

Section: Discussionmentioning

confidence: 99%

Chickenpox Associated Retinitis and Occlusive Vasculitis: A Case Report and Literature Review

et al. 2022

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Either retinitis and occlusive vasculitis are rare but vision threatening ocular complications of chickenpox in children. In this case report a 13-year-old girl who developed chickenpox 2 days before complaining with visual loss in her right eye is presented. She was vaccinated one dose of varicella zoster virus (VZV) vaccine when she was 12 months old. Best corrected visual acuity was counting fingers at 1.5 m in right eye. A subtle anterior segment inflammation and mild vitritis were observed. Fundoscopic examination of right eye showed ischemia in paracentral macula and white foci of retinitis along the superotemporal branch of retinal vessels. She was hospitalized and intravenous acyclovir treatment at 3 × 10 mg/kg daily dose was started. Serum IgM and IgG for VZV were positive. Aqueous humor PCR test was also reported positive for VZV DNA. Oral methylprednisolone was added at a dose of 64 mg/day at the 3 rd day acyclovir treatment. Macular edema developed at 4 th week of treatment and bevacizumab was administered intravitreally. After 3 injections retinal edema subsided completely. At 6-month follow-up retinal ischemia in superotemporal periphery was observed and photocoagulation was added to treatment.

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“…A few cases in adults have also been reported. Azevedo et al 14 and Galbussera et al 15 reported cases of optic neuritis following chicken pox in adults. Ihanamaki et al 16 reported a case of parainfectious bilateral optic neuritis associated with echoviral meningitis in an adult patient.…”

Section: Discussionmentioning

confidence: 99%

Encephalitis followed by optic neuritis: A case report and review of literature

Hasan¹,

Basri²,

Hin³

et al. 2013

Pak J Med Sci

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Encephalitis has been included in the causes of optic neuritis, but post encephalitic optic neuritis has been rarely reported. Majority of the cases of optic neuritis are either idiopathic or associated with multiple sclerosis, especially in western countries. This is very important in the Asian population where the incidence and prevalence of multiple sclerosis is not as high as in the Western countries. Although post infectious optic neuritis is more common in children, it can also be found in adults and is usually seen one to three weeks after a symptomatic infective prodrome. Here, we present a case of a 48 year-old-male who developed optic neuritis following viral encephalitis. His first presentation was with severe headache of two weeks duration. Viral encephalitis was diagnosed and treated. The patient presented again three weeks later with right eye pain and other features typical of optic neuritis. Corticosteroid therapy facilitated prompt recovery. Optic neuritis is an uncommon manifestation of encephalitis. It is important that both doctors and patients remain aware of post infectious cause of optic neuritis, which would enable a timely diagnosis and treatment of this reversible cause of vision loss.

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Optic Neuritis in an Adult Patient with Chickenpox

Cited by 6 publications

References 7 publications

Neuro-Ophthalmic Visual Impairment in the Setting of COVID-19

Neuro-Ophthalmic Visual Impairment in the Setting of COVID-19

Chickenpox Associated Retinitis and Occlusive Vasculitis: A Case Report and Literature Review

Encephalitis followed by optic neuritis: A case report and review of literature

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