Optical and Physical Properties of Silicone Oil Extracted from the Vitreous of Patients Who Underwent Vitrectomy for Retinal Detachment

Al-Dwairi, Rami; Aleshawi, Abdelwahab; Bani-Salameh, Areen A.; Aljarrah, Ihsan A.; Al‐Bataineh, Qais M.; Mohidat, Hasan; Sharie, Ahmed H. Al

doi:10.1089/jop.2022.0081

Cited by 7 publications

(10 citation statements)

References 50 publications

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“…Previous experiments have been conducted utilizing spectrometers with varying wavelengths and refractive index meters in order to investigate the optical characteristics of SiO in various scenarios, including both used and unused SiO, oils with different viscosities, different durations of intraocular SiO retention, as well as different surgical indications and related procedures. 8,9 Previous research has indicated that eyes containing fresh, non-emulsified SiOs exhibit increased transmittance and decreased reflectance of light within the visible spectrum. Additionally, these eyes demonstrate a higher refractive index.…”

Section: Discussionmentioning

confidence: 99%

“…As the emulsification process progresses, there is a gradual decrease in transmittance and an increase in reflectance within the visible spectrum of light, accompanied by a reduction in the refractive index. 8,9 Several factors have been identified that can expedite the process of emulsification. These factors encompass characteristics such as reduced interfacial surface tension, decreased viscosity, increased presence of low molecular weight siloxane compounds or other impurities, and the assimilation of diverse biological substances from intraocular fluids and tissues.…”

Section: Discussionmentioning

confidence: 99%

“…However, there is a noticeable lack of information regarding the optical properties of SiO, including both emulsified and non-emulsified forms. 2,8,9 Additionally, the literature lacks comprehensive insights into the efficacy of different retinal imaging techniques for detecting SiO.…”

Section: Introductionmentioning

confidence: 99%

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Multicolour® imaging findings in residual emulsified silicone oil bubbles

Venkatesh,

Joshi,

Choudhary

et al. 2024

European Journal of Ophthalmology

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Purpose To describe the findings of Multicolour® imaging (MCI) in the presence of residual emulsified silicone oil (SiO) droplets. Case report A 62-year-old man had previously undergone surgery for a traumatic retinal detachment in the left eye, followed by SiO removal a few years ago. His presenting visual acuity was 6/60 in the left eye and intraocular pressure was 12 mm Hg. Clinical examination revealed the presence of emulsified residual SiO droplets in the vitreous cavity, ‘inverse hyperoleon’ at the posterior pole and pathological myopia. Retinal findings were documented using optical coherence tomography (OCT), fundus autofluorescence (FAF), and MCI on the Spectralis (Heidelberg, Germany) machine. Results On OCT, the emulsified SiO droplets in the preretinal and intraretinal layers appeared as multiple hyperreflective dots with no underlying shadowing trapped beneath the residual posterior hyaloid or preretinal membrane in the region of the posterior staphyloma. Residual emulsified silicon oil on the retinal surface appeared to have greenish hue on the composite multicolour image and was hyperreflective on individual blue and green reflectance images and dark and hyporeflective on the infrared reflectance image. The SiO droplets appeared dark and were difficult to identify on the short wavelength FAF image. Conclusion To the best of our knowledge, this case report describes the MCI findings in emulsified SiO droplets for the first time.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Multicolour® imaging findings in residual emulsified silicone oil bubbles

Venkatesh,

Joshi,

Choudhary

et al. 2024

European Journal of Ophthalmology

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“…In addition, it may contribute to band keratopathy, secondary glaucoma, and visual disturbance, even after silicone oil removal. 30 The tendency to emulsify is determined by several factors, including interfacial surface tension, viscosity, chemical structure, the content of low molecular weight (MW) siloxane compounds or other impurities, and absorption of several biological substances from intraocular fluids and tissues (known as emulsifiers). 6 Blood, proteins, lipids, and ionized solutions (eg, biological fluids) are all elements that might diminish surface tension and so cause emulsification when silicone oil is injected into the vitreous cavity.…”

Section: Introductionmentioning

confidence: 99%

Silicone Oil Utilized in Pars Plana Vitrectomy for Patients with Advanced Proliferative Diabetic Retinopathy: Physico-Chemical and Optical Properties

Al-Dwairi,

Ahmad,

Aleshawi

et al. 2023

OPTH

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Objective Silicone oils have the role in maintaining the attachment of the retina in conditions where the risk of retinal re-detachment is high. However, silicone oils have the tendency to emulsify with subsequent complications. In this work, analyses have been performed to understand changes that occurred to the optical, and physical characteristics of the oil after removal from the vitreous cavity of patients underwent pars plana vitrectomy (PPV) for fibrovascular membranes/tractional retinal detachment (FVM/TRD). Methods Four samples of silicone oil were allocated from patients who underwent PPV for FVM/TRD. The Fourier-transform infrared (FTIR) spectroscopy, micro-viscometry, and ultraviolet-visible spectrometer analyses were utilized to determine the changes in its chemical bondings, viscosity, absorbance, transmittance, buoyance, and specific gravity. Results The mean age of the patients was 49.0 years. The mean duration of silicone oil implantation was 18.9 months. FTIR analysis showed significant breaking in the chemical bonding that was related to the lens status during the primary PPV, the presence of significant retinal hemorrhages, the duration of silicone oil implantation, and the degree of silicone oil filling. Similarly, viscosity and contact angle analyses revealed a reduction in the viscosity with similar factors to the FTIR analysis. Moreover, absorbance and transmittance were largely affected by the aggressiveness of FVM/TRD. Conclusion This study revealed that certain factors such as the age of the patient, duration of silicone oil implantation, lens status, and the presence of retinal hemorrhages, the degree of silicone oil filling and aggressiveness of FVM/TRD may contribute to the emulsification process.

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“…[1][2][3][4][5] With the improvements in ophthalmic microsurgery technology, vitrectomy combined with cataract surgery for diabetic retinopathy has become the main surgical method, [6,7] and most patients need to be filled with silicone oil after vitrectomy. [8][9][10] However, whether an intraocular lens (IOL) should be implanted in stage I after vitrectomy in patients with diabetic retinopathy or stage II implantation during silicone oil filling has been controversial, and there has been no systematic review of this clinical issue. Therefore, to guide clinicians in this surgical approach, we systematically reviewed the efficacy and safety of stage I and II IOL implantation for vitrectomy in patients with diabetic retinopathy.…”

Section: Introductionmentioning

confidence: 99%

Systematic review of the efficacy and safety of stage I or II IOL implantation in patients with diabetic retinopathy

Meng

Wang

et al. 2022

Medicine

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Background: Intraocular lens (IOL) implantation is required after vitrectomy combined with cataract surgery in diabetic retinopathy patients. However, the question of whether an IOL should be implanted in stage I after vitrectomy or stage II during silicone oil filling has been controversial, and there has been no systematic review of this clinical issue. Methods: WanFang, SinoMed CNKI, VIP, PubMed, Embase, and Cochrane Library databases were systematically searched for relevant studies. The deadline was May 8, 2021. All studies of stage I or II IOL implantation in patients with diabetes who underwent vitrectomy were included. Revman 5.3 software was used for the meta-analysis. Results: Four studies, involving 253 eyes, were included. This study analyzed the literature with a common outcome index by meta-analysis and systematically evaluated the literature without a common outcome index. Four studies compared the efficacy and safety of the 2 sequential surgical methods in patients with diabetic retinopathy. The results of the meta-analysis showed that there was no significant difference in the efficacy and safety of stage II IOL implantation when compared with stage I IOL implantation ( P > .05). One study showed that stage II cataract surgery with oil extraction resulted in better postoperative visual acuity and fewer complications than stage I cataract surgery with vitrectomy. One study showed that stage II IOL implantation during oil extraction had better postoperative visual acuity than stage I IOL implantation during vitrectomy without increasing surgical complications. Conclusion: Vitrectomy combined with stage II IOL implantation is safer and more effective than stage I in patients with diabetic retinopathy; however, more clinical studies are needed to verify this.

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Optical and Physical Properties of Silicone Oil Extracted from the Vitreous of Patients Who Underwent Vitrectomy for Retinal Detachment

Cited by 7 publications

References 50 publications

Multicolour® imaging findings in residual emulsified silicone oil bubbles

Multicolour® imaging findings in residual emulsified silicone oil bubbles

Silicone Oil Utilized in Pars Plana Vitrectomy for Patients with Advanced Proliferative Diabetic Retinopathy: Physico-Chemical and Optical Properties

Systematic review of the efficacy and safety of stage I or II IOL implantation in patients with diabetic retinopathy

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