2014
DOI: 10.1152/physiol.00002.2014
|View full text |Cite
|
Sign up to set email alerts
|

Optical Coherence Tomography in Respiratory Science and Medicine: From Airways to Alveoli

Abstract: Optical coherence tomography is a rapidly maturing optical imaging technology, enabling study of the in vivo structure of lung tissue at a scale of tens of micrometers. It has been used to assess the layered structure of airway walls, quantify both airway lumen caliber and compliance, and image individual alveoli. This article provides an overview of the technology and reviews its capability to provide new insights into respiratory disease.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
17
0
1

Year Published

2015
2015
2023
2023

Publication Types

Select...
7
1
1

Relationship

2
7

Authors

Journals

citations
Cited by 29 publications
(18 citation statements)
references
References 138 publications
0
17
0
1
Order By: Relevance
“…It has been especially helpful in measuring airway wall thickness and airway lumen area in patients with asthma and chronic pulmonary obstructive disease (Nakano et al, 2002). A rapidly emerging field is optical coherence tomography, which can be used to study lung structure at a scale of tens of micrometers, including individual alveoli (McLaughlin et al, 2014). Similar to MRI and HRCT, it can be used in vivo, which is a boon to respiratory physiologists and physicians.…”
Section: Magnetic Resonance Imaging and Computed Tomographymentioning
confidence: 99%
“…It has been especially helpful in measuring airway wall thickness and airway lumen area in patients with asthma and chronic pulmonary obstructive disease (Nakano et al, 2002). A rapidly emerging field is optical coherence tomography, which can be used to study lung structure at a scale of tens of micrometers, including individual alveoli (McLaughlin et al, 2014). Similar to MRI and HRCT, it can be used in vivo, which is a boon to respiratory physiologists and physicians.…”
Section: Magnetic Resonance Imaging and Computed Tomographymentioning
confidence: 99%
“…In the respiratory field, an increasing number of new applications for OCT are emerging 2 . Various endoscopic, needle and bench top OCT systems have been used to measure lumen dimensions in small 3 , large 4, 5 and upper airways 6 , to assess wall morphology and thickness 4, 7 , and to visualise individual alveoli 8 .…”
Section: Introductionmentioning
confidence: 99%
“…Several authors have explored the use of OCT for imaging various regions of the airway, both in humans 6, 4, 12 and in animal models 5, 10, 16 . In these studies, aOCT imaging was typically performed under static conditions (for instance at the end of expiration).…”
Section: Introductionmentioning
confidence: 99%