Quantum‐dot cellular automata (QCA) are prospective nanotechnology with striking performance to tackle the shortcomings of complementary metal‐oxide‐semiconductor (CMOS) transistor‐based technology such as fabrication dimensions and switching speed. The demultiplexer, as a crucial component for the design of many logic circuits, comprises a circuit for separating the multiplex data into the component data. The demultiplexer is highly utilised in the communication system for building serial data lines to parallel ones. So, its efficient schematisation has turned to an issue that has captured the concentration of the investigation group. Therefore, a novel structure of QCA‐based one to two demultiplexers is proposed, and it is employed to design one to four demultiplexers. QCAdesigner software, as a powerful layout and tool for simulation, is utilised for evaluating the validity and practicality of the proposed structures. The detailed evaluation of proposed layouts shows excellent performance than prior operations, and notable developments regarding the occupied area, cell count, and latency.