A bs tr ac t Friction-based dampers can be considered as one of the suitable passive control systems for seismic strengthening and rehabilitation of existing substandard structures due to their high adjustability and good energy dissipation capability. One of the main issues in the design of these systems is to obtain the magnitude of t h e ma xi mu m slip force and the distribution of slip forces along the height of the building. In this study, a practical performance-based optimisation methodology is developed for seismic design of RC frame buildings with friction energy dissipation devices, which allows for an accurate solution at low computational cost. The proposed method a ims at distributing the slip loads of the friction dampers to achieve a uniform distribution of damage along the height of the building. The efficiency of the method is evaluated through the optimum design of five different low to high-rise RC frames equipped with friction wall dampers under six natural and six synthetic spectrum-compatible earthquakes. Sensitivity analyses are performed to assess the reliability of the method using different initial height-wise slip load distributions, convergence parameters and earthquake records. The results indicate that optimum frames exhibit less maximum inter-storey drift (up to 43%) and global damage index (up to 75%), compared to uniform slip load distribution. The method is then developed to obtain the optimum design solution for a set of earthquakes representing a design spectrum. It is shown that the proposed method can provide an efficient tool for optimum seismic design of RC structures with friction energy dissipation devices for practical purposes.