Optimisation of carbon nanotubes for advanced diagnosis and biomedical application

Parwez, Khalid; Budihal, Suman V.

doi:10.1504/ijnp.2019.102602

Cited by 2 publications

(1 citation statement)

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“…These fillers disperse themselves within the fiber and provide high strength and toughness to the composite. This simulating behavior of the fillers make them a good candidate for the application such as tissue engineering, filtration, and advance nanofibers [30][31][32][33][34].…”

Section: Review Of Literaturementioning

confidence: 99%

Carbon Nanotubes Integrated Hydroxyapatite Nano-Composite for Orthopaedic and Tissue Engineering Applications

Parwez¹,

Bhagwath²,

Zawed³

et al. 2021

21st Century Advanced Carbon Materials for Engineering Applications - A Comprehensive Handbook

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The reassessment of the literature stipulates that an increasing amount of research in exploring the Hydroxyapatite Carbon Nanotubes (HA-CNT) system for orthopedic application. Chemical precipitation, CNT functionalization, and spray drying are the routinely used methods for CNT dispersal in HA matrix for the application such as bone tissue engineering, nanostructured scaffolds, dental regeneration, myocardial regeneration, and skin regeneration. Although mechanical strength and biocompatibility is a substantial concern for the fabrication of structures. Developing composite and bioceramic scaffolding with different natural and synthetic biomaterials are the futuristic approach in the biomedical engineering field. The problems such as biocompatibility, biodegradability, and mechanical resistance can be solved by combining natural, and artificial biomaterials. The natural biomaterials, such as collagen, cellulose, chitosan, have a close resemblance to the natural extracellular matrix (ECM). These materials are biocompatible, biodegradable. The artificial biomaterials, such as Poly Vinyl Pyrrolidone (PVP), Poly Capro Lactone (PCL), Poly Ethylene Glycol (PEG), and Poly Lactic Acid (PLA) are also the material of choice for the fabrication of the composite materials. Additional effort is necessary to fabricate biocompatible composite scaffolding for tissue engineering. Moreover, vascularization, differentiation, cellular proliferation, and cells to scaffold interaction are the foremost challenges in the area of tissue engineering that remains to overcome.

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