Ventilation system affects the water evaporation rate, energy consumption and the paper quality, which is considered as the largest optimization potential part of multi-cylinder dryer section. Energy consumption of drying system is divided into three parts: steam consumption of cylinders, steam consumption of air heaters, power consumption of blowers and exhaust fans. An energy consumption model of drying system integrating steam condensation system and ventilation system is constructed according to the control logic and process flow of the actual ventilation system, by combining the established models of each module and energy consumption indexes. It is the premise to realize the intelligent control of paper drying process. The research results perfects the mechanism of ventilation system for assisted drying, which can promote the improvement of the monitoring, and enable intelligent computing technology to play a greater role in optimizing drying operation and reducing drying energy consumption.