Optimization of Curcuminoids Extraction for Evaluation Against Parkinson’s Disease in Rats

Metabolomic profiling to reveal the therapeutic potency of Posidonia oceanica nanoparticles in diabetic rats

“…Total flavonoids and phenols were estimated in different extracts using the methods reported by Hamed et al 11 and the DPPH (1,1-diphenyl-2-picrylhydrazyl, 250 mM) radical scavenging assay was performed as described by Shimada et al 12 Briefly, the percentage inhibition of the DPPH radical was calculated according to the following formula: % inhibition = [( A control − A sample )/ A control ] × 100, where A is the absorbance at 517 nm. α-Glucosidase inhibitory activity was measured according to the method described by Elya et al 13 …”

Curcuminoids, a major turmeric component, have a sleep-enhancing effect by targeting the histamine H1 receptor

“…Owing to the poor solubility of curcuminoids in water, EtOAc is commonly used to isolate curcuminoids from turmeric. 19 Hamed et al ., 20 reported that the EtOAc fraction of turmeric has the highest curcuminoid content among other solvent fractions. Considering these findings, we first tested the sleep-enhancing effect of the EtOAc fractions of TE in a pentobarbital-induced sleeping animal model.…”

Profiling of secondary metabolites and DNA typing of three different Annona cultivars grown in Egypt

“…54. Total flavonoids and polyphenols were assessed according to (Hamed et al, 2019 ), whereas total alkaloids were determined according to (El-Gengaihi et al, 2020 ).…”