Optimization of extraction methods for the analysis of PFOA and PFOS in the salty matrices during the wastewater treatment

Liu, Yang; Bao, Jia; Hu, Xiaomin; Lu, Gui-Lin; Yu, Wenjing; Meng, Zhenhao

doi:10.1016/j.microc.2020.104673

Cited by 19 publications

(3 citation statements)

References 29 publications

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“…The compounds analyzed covered a wide range of polarities, from very polar substances, such as some of the short‐chain perfluoroalkyl substances (PFPeA), to non‐polar ones such as aryl phosphate or long alkyl chain phosphorus compounds (TBEP). In particular, due to the strong ionization performance of PFASs, they cannot be directly extracted from biological samples by organic solvents and cannot be retained on a C 18 chromatographic column 34 . The added ion pairing reagent, TBAHs, can be combined with PFASs to form paired ions and reduce its ionization characteristics.…”

Section: Resultsmentioning

confidence: 99%

“…In particular, due to the strong ionization performance of PFASs, they cannot be directly extracted from biological samples by organic solvents and cannot be retained on a C 18 chromatographic column. 34 The added ion pairing reagent, TBAHs, can be combined with PFASs to form paired ions and reduce its ionization characteristics. This combination enabled PFASs and OPFRs to be extracted by organic solvents at the same time.…”

Section: Instrumental Analysismentioning

confidence: 99%

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Simultaneous determination of poly‐ and perfluoroalkyl substances and organophosphorus flame retardants in serum by ultra‐performance liquid chromatography/tandem mass spectrometry

et al. 2022

Rapid Comm Mass Spectrometry

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Rationale Poly‐ and perfluoroalkyl substances (PFASs) and organophosphorus flame retardants (OPFRs) are two types of emerging organic pollutants with potential human health hazards. Here, a rapid and sensitive method was developed for the determination of sixteen PFASs and seven OPFRs in human serum by ultra‐performance liquid chromatography/tandem mass spectrometry (UPLC/MS/MS). Methods After optimizing the chromatographic and mass spectrometric conditions, respectively, 100 μL of serum sample was liquid–liquid extracted using 8 mL of methyl tert‐butyl ether. The 23 targets were quantified within 8 min. All targets were quantified by the isotope‐internal standard method in both negative‐ and positive‐ion mode by UPLC/MS/MS. Results The method was validated in terms of sensitivity, linearity, precision, and accuracy. The limit of detection ranged between 0.004 and 0.650 ng/mL. Recoveries ranged from70.0% to 118.9% with a relative standard deviation lower than 20%. The developed method was successfully applied to analyze targeted analytes in human serum samples. A total of 13 of 23 analytes were detected in over 50% of samples. Conclusions A sensitive and rapid method was developed to quantify sixteen PFASs and seven OPFRs in serum. Sensitivity, linearity, recovery, and precision were validated and found to be satisfactory. This method can be a valuable tool for evaluation of exposure to both PFASs and OPFRs with high separation efficiency and sensitivity.

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Section: Resultsmentioning

confidence: 99%

Section: Instrumental Analysismentioning

confidence: 99%

Simultaneous determination of poly‐ and perfluoroalkyl substances and organophosphorus flame retardants in serum by ultra‐performance liquid chromatography/tandem mass spectrometry

et al. 2022

Rapid Comm Mass Spectrometry

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“…For appropriate monitoring of the concentration of PFAS pollutants, knowledge of any matrix effects is important because the matrix components might alter the electrochemical signal of the analyte. [92][93][94] These impacts may be due to one or more of the following reasons: a) interaction between the analyte and other components of a sample which sequester the analyte making it unavailable for detection, b) interaction of matrix components with the sensing interface, which makes it more difficult to sense the analyte, and c) overlap of transfer potential of matrix components and the analyte of interest. Accordingly, for the development of a PFOA sensor, a matrix effect study is very important.…”

Section: Study Of Matrix Effects On Electrochemical Response Of Pfoamentioning

confidence: 99%

Ion-transfer electroanalytical detection of perfluorooctanoic acid at a liquid–liquid micro-interface array

Lamichhane

Arrigan

2023

Sens. Diagn.

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Green Analytical Chemistry Metrics and Life-Cycle Assessment Approach to Analytical Method Development

Abdelrahman

2022

Green Chemical Analysis and Sample Preparations

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Optimization of extraction methods for the analysis of PFOA and PFOS in the salty matrices during the wastewater treatment

Cited by 19 publications

References 29 publications

Simultaneous determination of poly‐ and perfluoroalkyl substances and organophosphorus flame retardants in serum by ultra‐performance liquid chromatography/tandem mass spectrometry

Simultaneous determination of poly‐ and perfluoroalkyl substances and organophosphorus flame retardants in serum by ultra‐performance liquid chromatography/tandem mass spectrometry

Ion-transfer electroanalytical detection of perfluorooctanoic acid at a liquid–liquid micro-interface array

Green Analytical Chemistry Metrics and Life-Cycle Assessment Approach to Analytical Method Development

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