Optimization of green extraction of phytochemicals from red grape pomace by homogenizer assisted extraction

Eyiz, Vildan; Tontul, İsmail; Türker, Selman

doi:10.1007/s11694-019-00265-7

Cited by 34 publications

(20 citation statements)

References 30 publications

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“…The extraction of flavonoids has also been favored in these mixtures thanks to the fact that the DES contains components such as chlorides-choline and lactic acid that can be linked by hydrogen bonds with the polyphenols; in addition, the effectiveness in the solubility in mixtures of glycerol-water can be explained due to the electrical permittivity of water which is modified by glycerol favoring the solubility of polyphenols [ 213 ]. In this sense, glycerol is a good prospect to be used as a solvent owing to its nontoxicity and low cost with relevant results in the extraction of flavonoids in other methods such as homogenizer-assisted extraction [ 214 ].…”

Section: Electrical Force Methodsmentioning

confidence: 99%

Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Luna

Ramírez-Garza

Saldivar

2020

The Scientific World Journal

170

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The flavonoids are compounds synthesized by plants, and they have properties such as antioxidant, anticancer, anti-inflammatory, and antibacterial, among others. One of the most important bioactive properties of flavonoids is their antioxidant effect. Synthetic antioxidants have side toxic effects whilst natural antioxidants, such as flavonoids from natural sources, have relatively low toxicity. Therefore, it is important to incorporate flavonoids derived from natural sources in several products such as foods, cosmetics, and drugs. For this reason, there is currently a need to extract flavonoids from plant resources. In this review are described the most important parameters involved in the extraction of flavonoids by unconventional methods such as ultrasound, pressurized liquid extraction, mechanochemical, high hydrostatic pressure, supercritical fluid, negative pressure cavitation, intensification of vaporization by decompression to the vacuum, microwave, infrared, pulsed electric field, high-voltage electrical discharges, and enzyme-assisted extraction. There are no unified operation conditions to achieve high yields and purity. Notwithstanding, progress has been achieved in the development of more advanced and environmentally friendly methods of extraction. Although in literature are found important advances, a complete understanding of the extraction process in each of the unconventional techniques is needed to determine the thermodynamic and kinetic mechanisms that govern each of the techniques.

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Section: Electrical Force Methodsmentioning

confidence: 99%

Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Luna

Ramírez-Garza

Saldivar

2020

The Scientific World Journal

170

View full text Add to dashboard Cite

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“…Incorporation of tartaric acid in this solvent up to 2% ( w / v ) disfavored increases in extraction yield and antioxidant activity of the extracts [ 36 ]. However, homogenizer-assisted extraction of red grape pomace indicated 50% ( w / v ) glycerol concentration as being the optimum for maximizing total polyphenol, total flavonoid and pigment extraction yield [ 45 ]. A concomitant maximization was also seen for the antioxidant activity of the extract obtained.…”

Section: Use Of Glycerol In Solid-liquid Extraction Of Polyphenolimentioning

confidence: 99%

Glycerol and Glycerol-Based Deep Eutectic Mixtures as Emerging Green Solvents for Polyphenol Extraction: The Evidence So Far

Makris

Lalas

2020

Molecules

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The acknowledgement that uncontrolled and excessive use of fossil resources has become a prime concern with regard to environmental deterioration, has shifted the orientation of economies towards the implementation of sustainable routes of production, through the valorization of biomass. Green chemistry plays a key role in this regard, defining the framework of processes that encompass eco-friendly methodologies, which aim at the development of highly efficient production of numerous bioderived chemicals, with minimum environmental aggravation. One of the major concerns of the chemical industry in establishing sustainable routes of production, is the replacement of fossil-derived, volatile solvents, with bio-based benign ones, with low vapor pressure, recyclability, low or no toxicity, availability and low cost. Glycerol is a natural substance, inexpensive and non-toxic, and it is a principal by-product of biodiesel industry resulting from the transesterification process. The ever-growing market of biodiesel has created a significant surplus of glycerol production, resulting in a concomitant drop of its price. Thus, glycerol has become a highly available, low-cost liquid, and over the past decade its use as an alternative solvent has been gaining unprecedented attention. This review summarizes the utilization of glycerol and glycerol-based deep eutectic mixtures as emerging solvents with outstanding prospect in bioactive polyphenol extraction.

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“…Several studies reported that water-glycerol mixtures were more efficient extraction media than water. Examples include the UAE of chlorogenic acid and other caffeic acid derivatives from spent filter coffee [37] and polyphenols from red grape pomace [38].…”

Section: Effect Of Uae Variables On Phenolic Acid Extraction Yieldmentioning

confidence: 99%

Comparison of Maceration and Ultrasonication for Green Extraction of Phenolic Acids from Echinacea purpurea Aerial Parts

et al. 2020

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Echinacea purpurea is used in herbal medicinal products for the prevention and treatment of the common cold, as well as for skin disorders and minor wounds. In this study, the efficiency of traditional maceration using water and ethanol was compared with the maceration using mixtures of water and glycerol, a non-toxic, biodegradable solvent from renewable sources. It was found that the glycerol–water mixtures were as effective as ethanol/water mixtures for the extraction of caffeic acid derivatives. All the prepared extracts demonstrated notable antiradical properties. Furthermore, an efficient ultrasound-assisted extraction using glycerol–water mixtures was developed using six independent variables. Their levels needed for the maximum extraction of caffeic acid derivatives were as follows: glycerol 90% (m/m), temperature 70 °C, ultrasound power 72 W, time 40 min, and ascorbic acid 0 mg/mL. Under the optimized conditions, ultrasound-assisted extraction was superior to maceration. It achieved significantly higher yields of phenolic acids in shorter extraction time. The presence of zinc in plant material may contribute to the beneficial effects of E. purpurea preparations. Since glycerol is a non-toxic solvent with humectant properties, the prepared extracts can be directly used for the preparation of cosmetics or oral pharmaceutical formulations without the need for solvent removal.

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Optimization of green extraction of phytochemicals from red grape pomace by homogenizer assisted extraction

Cited by 34 publications

References 30 publications

Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Glycerol and Glycerol-Based Deep Eutectic Mixtures as Emerging Green Solvents for Polyphenol Extraction: The Evidence So Far

Comparison of Maceration and Ultrasonication for Green Extraction of Phenolic Acids from Echinacea purpurea Aerial Parts

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