Optimization of the enzyme-catalyzed synthesis of amino acid-based surfactants from palm oil fractions

Soo, Ee Lin; Salleh, Abu Bakar; Basri, Mahiran; Rahman, Raja Noor Zaliha Raja Abdul; Kamaruddin, Kamarulzaman

doi:10.1016/s1389-1723(03)80068-3

Cited by 37 publications

(11 citation statements)

References 19 publications

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“…The percentage yield was increased with increasing temperature from 30-50 . This is due to the fact that, energy received from heat of higher temperature was used to increase the frequency of collision between the molecules (13). The percentage yield was at optimum at 45-50 (94.54%-96.02%).…”

Section: Resultsmentioning

confidence: 99%

Large Scale Production of Liquid Wax Ester by Immobilized Lipase

et al. 2005

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Oleyl oleate, a liquid wax ester was synthesized by an immobilized Candida antartica lipase B (Novozym 435) as biocatalyst using oleic acid and oleyl alcohol. The effects of various reaction parameters were optimized to obtain a high yield of liquid wax esters. Investigation in large scale production was performed in batch mode of stirred tank reactor (STR) with one multi-bladed impeller. The optimum condition to produce liquid wax ester was, reaction time (RT); 30 min, temperature (T); 50 , amount of enzyme (E); 90 g (900,000 PLU), agitation speed (A) of 400 rpm, number of impeller tip (N) of 2 and molar ratio of oleyl alcohol to oleic acid (M); 2:1. Analysis of the yield showed that at optimum condition, 90% liquid wax esters were produced. The stability of Novozym 435 showed at high percentage ( 80%) up to 4 cycles.

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Section: Resultsmentioning

confidence: 99%

Large Scale Production of Liquid Wax Ester by Immobilized Lipase

et al. 2005

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“…The development of an economical and environmentally friendly silkworm-based product is, therefore, urgently required. Research on the use of vegetable oil as a raw material to synthesize fatty acid chloride is dated to the last century, such as the use of soybean oil and lysine as the raw material to synthesize Nacyl lysine surfactant [33], and soy protein and palm oil as substrates for the synthesis of amino acid-based surfactants [3,34]. In terms of characteristics and applications of N-fatty acyl amino acid surfactant, there are many factors to be considered, including the high cost of oil and amino acid source.…”

Section: Discussionmentioning

confidence: 99%

Biosafety Evaluation of Three Sodium Lauryl N‐Amino Acids Synthesized from Silk Industrial Waste in Mice

Ding

Wan

Zhang

2017

J Surfact & Detergents

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In this study, three amino acid mixtures recovered from silk industry waste were reacted with lauryl chloride to synthesize three sodium laurel N‐amino acid surfactants. The three types of anionic surfactants are referred to as silk fibroin surfactant, silk sericin surfactant, and silkworm pupae surfactant. All three surfactants showed good surface properties. To evaluate biological safety, we added these three surfactants to the normal diet of mice for 8 weeks. Blood indices, blood lipid, antioxidant capacity (GSH‐PX, MDA, T‐AOC, and T‐SOD), and lipid metabolism key enzyme mRNA (PPAR‐γ, SREBP, FASN, and C/EBP‐α) levels in the liver were measured. No evident histopathological changes were found in the liver and kidney. The results showed no significant difference in their indexes between the surfactant‐fed and normal diet‐fed mice. Thus, the three amino acid surfactants are biologically safe and can be used in daily chemical cleaning products. These surfactants will not only help to reduce wastage of resources and damage to the environment, but also yield economic benefits to the silk industry in the future.

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“…are more soluble in water and consequently remove the essential water from the enzyme and disrupt its conformation with attendant deactivation (Soo et al, 2003). Several authors have reported the effect of solvents on the performance of enzymes and have shown that enzymes present better activity in media containing solvents with high Log P o/w values (Bemquerer et al, 1994;Koutinas et al, 2018;Lara and Park, 2004;Valivety et al, 1991;Zaks and Klibanov, 1985).…”

Section: Overview Of Criteria To Screen Solvents For An Industrial Bimentioning

confidence: 99%

Screening of organic solvents for bioprocesses using aqueous-organic two-phase systems

Grundtvig

Heintz

Krühne

et al. 2018

Biotechnology Advances

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The application of conventional organic solvents has been essential in several steps of bioprocesses in order to achieve sufficient economic efficiency. The use of organic solvents is frequently used either to partly or fully replace water in the reaction medium or as a process aid for downstream separation. Nowadays, manufacturers are increasingly requested to avoid and substitute solvents with hazardous potential. Therefore, the solvent selection must account for potential environmental hazards, health and safety problems, in addition to fulfilling the ideal characteristics for application in a process. For the first time, criteria including Environment, Health and Safety (EHS), as well as the technical requirements for reaction and separation have been reviewed, collected and integrated in a single organic solvent screening strategy to be used as a guideline for narrowing down the list of solvents to test experimentally. Additionally, we have also included a solvent selection guide based on the methodology developed in the Innovative Medicines Initiative CHEM21 (IMI CHEM21) project and applied specifically to water-immiscible solvents commonly used in bioprocesses.

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Optimization of the enzyme-catalyzed synthesis of amino acid-based surfactants from palm oil fractions

Cited by 37 publications

References 19 publications

Large Scale Production of Liquid Wax Ester by Immobilized Lipase

Large Scale Production of Liquid Wax Ester by Immobilized Lipase

Biosafety Evaluation of Three Sodium Lauryl N‐Amino Acids Synthesized from Silk Industrial Waste in Mice

Screening of organic solvents for bioprocesses using aqueous-organic two-phase systems

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