Optimization of the Laser/Cancer Treatment’s Planning and Thermal Dosimetry Control

Abstract

During the laser thermal ablation process, it is challenging to control the side effects and optimize the planning of the dosimetry process for all patients. A software tool would help physicians plan and manage the dosimetry process while predicting and organizing the treatment. This would maximize the therapeutic effect and minimize any side effects, so new strategies can be proposed and evaluated.In this paper, we propose a new dosimetry planning approach for the laser surgery/cancer treatment with physician interaction that takes into account all the steps of the management of the dosimetry process. Depending on the impact of the thermal damage to the tissue during the simulation, the software tool will output a dosimetry schedule for each simulation and keep all choices for a final decision.Using Client Server technology, the software tool will also include a public and shared knowledge database to keep track of all simulations and learning process. This will optimize the process by dropping all unwanted simulation by delimiting the tissue tumor size, probe size, laser power, and time range.A case study of the Laser Interstitial Thermal Therapy (LITT) will demonstrate the feasibility of the dosimetry framework. LITT can be a highly complex treatment, with many parameters influencing treatment efficacy.

Thermal Damage Modeling Analysis and Validation during Treatment of Tissue Tumors

“…The main purpose of this section is the implementation and validation of the theoretical results and volume simulation. The VHDL code will be put into the operation designed to facilitate the development of the architecture for their implementation in VLSI [14]- [17]. This architecture will be modeled in a high-level language and simulated to assess its performance and implemented on an FPGA.…”