Optimization of ultrasonic-assisted extraction of wedelolactone and antioxidant polyphenols from Eclipta prostrate L using response surface methodology

Fang, Xinsheng; Wang, Jianhua; Wang, Yingzi; Li, Xueke; Zhou, Hongying; Zhu, Lixiang

doi:10.1016/j.seppur.2014.10.007

Cited by 46 publications

(31 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, it is considered as adulterant for the proper drug E. prostrata in Indian system of medicine. In a previous study, higher level of total phenolic content of E. prostrata (2250 mg GAE / 100 g) was reported when compared to the results of present study, which might be due to the ultrasonic-assisted extraction process (Fang et al 2014). Quantification of total phenolic compounds using Folin's-Ciocaltue reagent (Spectrometric method) could help us to differentiate E. prostrata from W. calendulacea.…”

Section: Polyphenolic Contentcontrasting

confidence: 51%

Development of Chemical Fingerprints to Differentiate the Controversial Indian Herbal Drugs Eclipta Prostrata and Wedelia Calendulacea (Bhringraja)

Vadivel¹,

Anand²,

Monajkumar³

et al. 2017

Bull. Pharm. Res.

View full text Add to dashboard Cite

In Indian system of medicine, Eclipta prostrata is an important herbal ingredient of several Ayurvedic and Siddha formulations and it is commonly called as Bhringraja. But, this plant is often confused with Wedelia calendulacea, which is also known as Bhringraja and also being adulterated in Indian herbal market. In order to differentiate these plant drugs (Eclipta prostrata and Wedelia calendulacea), in the present work we have developed chemical fingerprints. Phytochemical analysis, UV-Visible, FT-IR and NMR spectroscopy, HPTLC and HPLC chromatography were carried out in the selected plant materials. Phytochemical analysis of methanolic extract of investigated materials showed that W. calendulacea contained higher level of total phenolic compounds (381.82 mg GAE/100 g) when compared to E. prostrata (105 mg GAE/100 g). Scanning in UV-Visible spectroscopy exhibited difference between selected samples, especially at 250-450 nm. Similarly, FT-IR spectroscopy of raw materials indicated notable difference between the samples at 400 -1000 cm -1 region. NMR spectroscopy illustrated remarkable difference between the chloroform extract of selected samples at 1-2 ppm region. HPTLC profile of methanolic extract of E. prostrata exhibited a total number of 9 peaks while W. calendulacea showed 12 number of peaks. Chemical profile investigated in the present study would be helpful to differentiate E. prostrata from W. calendulacea and also useful to prevent their adulteration in herbal industry.

show abstract

Section: Polyphenolic Contentcontrasting

confidence: 51%

Development of Chemical Fingerprints to Differentiate the Controversial Indian Herbal Drugs Eclipta Prostrata and Wedelia Calendulacea (Bhringraja)

Vadivel¹,

Anand²,

Monajkumar³

et al. 2017

Bull. Pharm. Res.

View full text Add to dashboard Cite

show abstract

“…AST is often called BLi hao^, BLou hao^or BLu hao^in China (Shi et al 2010) It has been used for thousands of years in China as vegetable to produce beverages, tea, fermented yoghurt and functional shampoo (Peng et al 2011). AST can also be used as medicine to diminish inflammation, stop bleeding, relieve a cough, flavor enhancer and act as appetizers (Fang et al 2014;Peng et al 2011). As a group of biologically active compositions, polysaccharides are well-known for their health-beneficial functions attributed to their anti-oxidant and anti-cancer activities (Li et al 2014a, b, c;Wu et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Ultrasound-assisted extraction of polysaccharides from Artemisia selengensis Turcz and its antioxidant and anticancer activities

Wang

Umair

et al. 2016

J Food Sci Technol

View full text Add to dashboard Cite

Artemisia selengensis Turcz (AST) is a perennial herb with therapeutic and economic applications in China. The effects of ultrasound-assisted extraction (UAE) parameters upon extraction yield (EY%), antioxidant and antitumor activities of the polysaccharides extracts were studied by using a factorial design and response surface methodology. The optimal conditions determined were as: ultrasonic power 146 W, extraction time 14.5 min. and extraction temperature 60°C. The average molecular weights of two homogeneous polysaccharides (APS1 and APS2) purified by DEAE cellulose-52 and Sephadex G-100 column chromatography were 125.4 and 184.1 kDa, respectively. Monosaccharide analysis showed that APS1 and APS2 were composed of five common monomers i.e., galactose, mannose, arabinose, xylose and rhamnose and one different monomer glucose and galacturonic acid respectively, with a most abundant part in molar % of APS1 and APS2 were glucose (83.01 %) and galacturonic acid (48.87 %) while least were xylose (0.80 %) and mannose (1.73 %) respectively. The antioxidant properties were determined by evaluating DPPH, hydroxyl radical scavenging activity and reducing power which indicated both APS1 and APS2 showed strong scavenging activities and anticancer activities on HT-29, BGC823 and antitumor activity on HepG-2. As UAE improved the polysaccharides yield than CSE, meanwhile, no significant difference of polysaccharides chemical compositions. Therefore, the present study suggests that the consumption of AST leaves may beneficial for the treatment of many diseases.

show abstract

“…Moreover, ultrasound-assisted extraction, as an innovative technology, could enhance mass and heat transfer by disrupting the matrix cell walls mechanically, through creation shear forces, to promote the release of bioactive components from natural products. 16,17 It has been reported that a variety of nutritional materials such as saponins, phenolics, polysaccharides, essential oils, and carotenoids have been extracted successively with the aid of ultrasound methods. 18,19 Once compared to conventional solvent extraction, ultrasound sonication is considered a useful, inexpensive method in addition it can increase extraction yield and extraction efficiency, thus a noticeable reduction in solvent consumption resulting in saving extraction time and energy input with high reproducibility.…”

Section: Introductionmentioning

confidence: 99%

Determination of Four Major Saponins in Skin and Endosperm of Seeds of Horse Chestnut (Aesculus Hippocastanum L.) Using High Performance Liquid Chromatography with Positive Confirmation by Thin Layer Chromatography

Abudayeh¹,

Azzam²,

Naddaf³

et al. 2015

Adv Pharm Bull

View full text Add to dashboard Cite

Optimization of ultrasonic-assisted extraction of wedelolactone and antioxidant polyphenols from Eclipta prostrate L using response surface methodology

Cited by 46 publications

References 25 publications

Development of Chemical Fingerprints to Differentiate the Controversial Indian Herbal Drugs Eclipta Prostrata and Wedelia Calendulacea (Bhringraja)

Development of Chemical Fingerprints to Differentiate the Controversial Indian Herbal Drugs Eclipta Prostrata and Wedelia Calendulacea (Bhringraja)

Ultrasound-assisted extraction of polysaccharides from Artemisia selengensis Turcz and its antioxidant and anticancer activities

Determination of Four Major Saponins in Skin and Endosperm of Seeds of Horse Chestnut (Aesculus Hippocastanum L.) Using High Performance Liquid Chromatography with Positive Confirmation by Thin Layer Chromatography

Contact Info

Product

Resources

About