This paper is the first to present the dynamic buckling behavior of spherical shell structures colliding with an obstacle block under the sea. The effect of deep water has been considered as a uniform external pressure by simplifying the effect of fluid–structure interaction. The calibrated numerical simulations were carried out via the explicit finite element package LS-DYNA using different parameters, including thickness, elastic modulus, external pressure, added mass, and velocity. The closed-form analytical formula of the static buckling criteria, including point load and external pressure, has been firstly established and verified. In addition, unprecedented parametric analyses of collision show that the dynamic buckling force (peak force), mean force, and dynamic force redistribution (skewness) during collisions are proportional to the velocity, thickness, elastic modulus, and added mass of the spherical shell structure. These linear relationships are independent of other parameters. Furthermore, it can be found that the max force during the collision is about 2.1 times that of the static buckling force calculated from the analytical formula. These novel insights can help structural engineers and designers determine whether buckling will happen in the application of submarines, subsea exploration, underwater domes, etc.