Optoelectronic Tweezers for the Manipulation of Cells, Microparticles, and Nanoparticles

Ohta, Aaron T.; Chiou, Pei-Yu; Jamshidi, Arash; Hsu, Hsan-Yin; Valley, Justin K.; Neale, Steven L.; Wu, Ming C.

doi:10.5772/6921

Cited by 2 publications

(2 citation statements)

References 72 publications

(84 reference statements)

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“…An OET device consists of several layers of elements. The top layer consists of an ITO transparent electrode; then there is a photoconductive electrode layer made out of amorphous silicon (a-Si:H) [139]. In an OET, light is projected into the device using the help of a digital projector and a digital micromirror device (DMD), then it passes through an objective lens directed towards the a-Si:H layer, where it creates the image of the projected light.…”

Section: Optoelectronic Tweezers (Oet)mentioning

confidence: 99%

“…Because of the use of a-Si:H (which is abundantly used in solar cells), the setup of OET is inexpensive compared to the optical tweezers system. However, this technique of creating a trap is not fully utilized in biomedical applications directly, but the separation of biological cells and, consequently, the medical diagnosis are proposed [139,140].…”

Section: Optoelectronic Tweezers (Oet)mentioning

confidence: 99%

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Light-Controlled Microbots in Biomedical Application: A Review

2022

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The advancement of micro-robotics in recent years has permitted a vast field of active research and application in the biomedical sector. Latest developments in microrobotics point to some ground-breaking work using light for manufacturing as well as actuation. Optical manipulation in three-dimensional space for living biological cells in a minimally invasive manner is crucial for different biomedical applications. This article attempts to provide an overview of the accomplishments and future possibilities of light-powered microbots. An overview of the feasibility of different fabrication techniques and control modalities is compared, along with prospective applications and design considerations of light-powered microbots. A variety of challenges that still prohibit polymeric light-powered microbots from attaining their full potential are pointed out, and viable ways to overcome such challenges are proposed. This study will help future researchers to study and develop the next generation of light-actuated microbots by overcoming the current limitations and challenges in fabrication, control, and design.

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Section: Optoelectronic Tweezers (Oet)mentioning

confidence: 99%

Section: Optoelectronic Tweezers (Oet)mentioning

confidence: 99%

Light-Controlled Microbots in Biomedical Application: A Review

2022

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Development of a joystick-controlled optically-induced dielectrophoresis platform for real-time micromanipulation

Sam

Liu

Wang

et al. 2013

2013 IEEE International Conference on Robotics and Biomimetics (ROBIO)

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Global efforts have been made in the past two decades to efficiently manipulate and assemble tiny entities at micro-scale or even nano-scale. In this paper, we discuss our elopment of adding an interactive controller to the emerging optically-induced dielectrophoresis (ODEP) platform which could be used to rapidly and parallelly manipulate micro and nano particles in fluidic medium. We have demonstrated that, with a real-time control interface via a joystick, users can intuitively use the platform to selectively trap and move a single 10um polystyrene micro-bead easily and move it at a maximum velocity of 347 m/s. The frequency spectrum, force and velocity in manipulating micro-beads are investigated to characterize this controller-integrated ODEP system. Through experimental investigation, we have verified that the smoothness of the light motion brings a limit to the speed in manipulating micro entities in a static fluidic medium. It is further shown that there is a possibility to increase the maximum manipulation speed by enhancing both the software and hardware refresh rates for the animated light image projected in an ODEP chip.

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Optoelectronic Tweezers for the Manipulation of Cells, Microparticles, and Nanoparticles

Cited by 2 publications

References 72 publications

Light-Controlled Microbots in Biomedical Application: A Review

Light-Controlled Microbots in Biomedical Application: A Review

Development of a joystick-controlled optically-induced dielectrophoresis platform for real-time micromanipulation

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