Optomechanical non-contact measurement of microparticle compressibility in liquids

Han, Kewen; Suh, Jeewon; Bahl, Gaurav

doi:10.1364/oe.26.031908

Cited by 7 publications

(5 citation statements)

References 27 publications

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“…In our experiments, silica MBRs were fabricated by the fuseand-blow technique. [16,20,52,53,[54][55][56] The optical WGM of the MBR was probed and pumped by a C-band CW tunable laser (Toptica CTL1550) via an optical tapered fiber (diameter of 1-3 𝜇m). The distance between the MBR and optical tapered fiber was controlled by a 3D nanopositioner with a resolution of 20 nm.…”

Section: Resultsmentioning

confidence: 99%

Optical Supercontinuum Generation via Rotational and Vibrational Molecular Cavity Optomechanics

Liao

Chen

et al. 2022

Laser & Photonics Reviews

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The solid high quality (Q) factor whispering gallery mode microcavities are demonstrated as an excellent experimental platform for enhanced light-matter interactions, and are applied in the studies of nonlinear optics, quantum optics, and sensing. However, the interaction between the microcavity and liquid anisotropic molecule, which is unique for abundant vibrational and rotational degrees of freedom, is rarely studied. Here, the gap is bridged by filling an optofluidic microbubble resonator with carbon disulfide, and the related anisotropic molecular cavity optomechanics effects are investigated. Due to the enhanced coupling between the optical mode and the rotation/vibration of molecules, stimulated Rayleigh-Kerr/Raman-Kerr scattering effects are observed. Molecular cavity optomechanics provides a broadband gain for generating Stokes photons in high-Q optical modes, and eventually allows quasi-supercontinuum generation with a bandwidth of 436 nm under a low continuous laser pump power of about 10 mW. This work opens a new avenue for strong light-matter interactions by exploring rotational and vibrational molecular cavity optomechanics, which provides a promising platform for nonlinear optics, cavity-enhanced molecular reorientation dynamics, and novel optical sources.

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Section: Resultsmentioning

confidence: 99%

Optical Supercontinuum Generation via Rotational and Vibrational Molecular Cavity Optomechanics

Liao

Chen

et al. 2022

Laser & Photonics Reviews

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“…Biological particles may have a high compressibility contrast with respect to the surrounding fluid; therefore, accessing the compressibility of the particle can add very valuable information for subsequent identification and analysis. Using an opto-mechano-fluidic resonator, Bahl et al managed to measure the compressibility of small particles based on the change in the frequency associated with radi-ally symmetric mechanical breathing modes of the resonator as the particle passes through it [108]. The formula that they proposed for the relative frequency shift contains the inertial term due to the mass and a new term including compression effects of the particle:…”

Section: Suspended Microchannel Resonatorsmentioning

confidence: 99%

A Review on Theory and Modelling of Nanomechanical Sensors for Biological Applications

et al. 2021

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Over the last decades, nanomechanical sensors have received significant attention from the scientific community, as they find plenty of applications in many different research fields, ranging from fundamental physics to clinical diagnosis. Regarding biological applications, nanomechanical sensors have been used for characterizing biological entities, for detecting their presence, and for characterizing the forces and motion associated with fundamental biological processes, among many others. Thanks to the continuous advancement of micro- and nano-fabrication techniques, nanomechanical sensors have rapidly evolved towards more sensitive devices. At the same time, researchers have extensively worked on the development of theoretical models that enable one to access more, and more precise, information about the biological entities and/or biological processes of interest. This paper reviews the main theoretical models applied in this field. We first focus on the static mode, and then continue on to the dynamic one. Then, we center the attention on the theoretical models used when nanomechanical sensors are applied in liquids, the natural environment of biology. Theory is essential to properly unravel the nanomechanical sensors signals, as well as to optimize their designs. It provides access to the basic principles that govern nanomechanical sensors applications, along with their intrinsic capabilities, sensitivities, and fundamental limits of detection.

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“…To overcome this problem, physical parameter-based sensors have been proposed as a promising alternative. They have been used for non-selective fluid discerning [ 4 ] and characterization of density [ 5 ], refractive index [ 6 , 7 ] or compressibility [ 8 , 9 ] of analytes in a liquid environment. By using these physical sensors, it is also possible to track in real-time the changes in the physical properties of fluid mixtures with varying concentrations of their components [ 10 , 11 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Nanomechanical Molecular Mass Sensing Using Suspended Microchannel Resonators

Martín-Pérez

Ramos

Tamayo

et al. 2021

Sensors

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In this work we study the different phenomena taking place when a hydrostatic pressure is applied in the inner fluid of a suspended microchannel resonator. Additionally to pressure-induced stiffness terms, we have theoretically predicted and experimentally demonstrated that the pressure also induces mass effects which depend on both the applied pressure and the fluid properties. We have used these phenomena to characterize the frequency response of the device as a function of the fluid compressibility and molecular masses of different fluids ranging from liquids to gases. The proposed device in this work can measure the mass density of an unknown liquid sample with a resolution of 0.7 µg/mL and perform gas mixtures characterization by measuring its average molecular mass with a resolution of 0.01 atomic mass units.

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Optomechanical non-contact measurement of microparticle compressibility in liquids

Cited by 7 publications

References 27 publications

Optical Supercontinuum Generation via Rotational and Vibrational Molecular Cavity Optomechanics

Optical Supercontinuum Generation via Rotational and Vibrational Molecular Cavity Optomechanics

A Review on Theory and Modelling of Nanomechanical Sensors for Biological Applications

Nanomechanical Molecular Mass Sensing Using Suspended Microchannel Resonators

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