Purpose: To assess the reproducibility (i.e., inter-device reliability) of the biometers Topcon MYAH, Oculus MyopiaMaster and Haag-Streit Lenstar LS 900 with the Carl Zeiss IOLMaster 700 and the intrasubject repeatability in myopic children to reliably detect axial growth for myopia management. Methods: 22 myopic children (11.1 ± 2.4 yr) with a spherical equivalent of -3.53 ± 2.35 D were subject to each of the biometers to assess axial length (AL), corneal parameters (steepK, flatK, meanK, vectors J0, J45), of which 16 children agreed to a second round of measurements. Reproducibility of the first measurements between the IOLMaster and every other biometer was assessed employing a Bland-Altman approach and paired Student t-test. Repeatability was assessed as intra-subject standard deviation and was used to estimate the minimum time interval required between two axial length measurements to reliably detect axial growth of an eye of at least 0.1 mm/year. Results: Repeatability for AL measurements was IOLMaster: 0.05 mm, MyopiaMaster: 0.06 mm, Myah: 0.06 mm, Lenstar: 0.04 mm; the respective minimal time interval for axial growth assessment in myopia management was estimated as 5.6, 6.6, 6.7, and 5.0 months, respectively. Best reproducibility in AL measurement was found between IOLMaster and Lenstar (95% Limits of Agreement (LoA) for reproducibility -0.06 to 0.02). As for the means, Lenstar measures AL longer than IOLMaster by 0.02 mm (p<0.001). MyopiaMaster measures meanK significantly lower (by 0.21 D with p<0.001) than IOLMaster. Regarding J0, all biometers deviate significantly from IOLMaster measurements (p<0.05).
Conclusion: A generally good agreement was observed between all the biometers. When assessing myopia progression in children a timeframe of at least six months between the AL measurements is advisable to reliably determine any deviation from a normal growth pattern.