2006
DOI: 10.1080/00016480500468976
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Oral and intralesional steroid therapy in giant cell granuloma

Abstract: Giant cell granulomas account for 7% of all benign tumors of the jaw. They are commonly seen as asymptomatic masses. A 4-year-old boy with an exophitic, crusty, hemorrhagic mass on the anterolateral region of the right maxilla was referred to our department. Pathological examination was reported as giant cell granuloma. A mixture of prednisolone, lidocaine and adrenaline was injected intralesionally once a week and oral fluocortone was added to this therapy. A limited surgery could be performed. Intralesional … Show more

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Cited by 27 publications
(10 citation statements)
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“…Cherubism has these mutations whereas central giant cell granuloma does not [9][10][11]; therefore these mutations may be important diagnostic criteria for both diseases. Furthermore, while subcutaneous injection of calcitonin and local injection of steroids are reported to be effective in treating central giant cell granuloma [12,13], treatment for cherubism is primarily follow-up, so examination of patients for the presence of mutations in the SH3BP2 gene is important for selecting a treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Cherubism has these mutations whereas central giant cell granuloma does not [9][10][11]; therefore these mutations may be important diagnostic criteria for both diseases. Furthermore, while subcutaneous injection of calcitonin and local injection of steroids are reported to be effective in treating central giant cell granuloma [12,13], treatment for cherubism is primarily follow-up, so examination of patients for the presence of mutations in the SH3BP2 gene is important for selecting a treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, both the destructive properties of the lesion and its aggressive management can result in significant functional and esthetic defects, what is particularly a concern in pediatric and young adult patients (12,13). In the last years, different nonsurgical treatments have been proposed.…”
Section: Discussionmentioning
confidence: 99%
“…Es una entidad relativamente rara. Supone un 7% de los tumores de los maxilares (siendo su localización preferente en la región de los incisivos, y más frecuentemente en la mandí-bula que en el maxilar) 2 . Es más habitual en niños y adultos jóvenes, con un ligero predominio en el sexo femenino 2 .…”
Section: Discussionunclassified