Oral candidiasis and angular cheilitis

Sharon, Victoria R.; Fazel, Nasim

doi:10.1111/j.1529-8019.2010.01320.x

Cited by 90 publications

(57 citation statements)

References 63 publications

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“…Angular cheilitis may be due to fungal infection but may also be caused by staphylococcal infection or anaemia. Factors favouring angular cheilitis are immunosuppression, tobacco smoking, endocrine disorders, [16]. Exfoliative cheilitis is also present in leukemias and HIV infections.…”

Section: Discussionmentioning

confidence: 99%

Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome

Błochowiak¹,

Olewicz‐Gawlik²,

Polańska³

et al. 2016

pdia

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Introduction One of the most important symptoms of Sjögren syndrome is xerostomia. The oral cavity deprived of saliva and its natural lubricative, protective and antibacterial properties is prone to a number of unfavourable consequences. Aim To present the most important lesions on the oral mucosa in primary and secondary Sjögren syndrome and in dry mouth syndrome. Material and methods The study group comprised 55 patients including 52 women and 3 men aged 20–72 years (average: 28.25 years). Results Basing on the accepted criteria, primary Sjögren syndrome was diagnosed in 22 (40%) patients, secondary Sjögren syndrome in 18 (32.7%) patients, and dry mouth syndrome in 15 (27.27%) patients. The physical examination and the examination of the mouth were performed and history was elicited from every patient. Conclusions The most common pathologies appearing on the oral mucosa in primary and secondary Sjögren syndrome are angular cheilitis, cheilitis, increased lip dryness as well as non-specific ulcerations, aphthae and aphthoid conditions.

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Section: Discussionmentioning

confidence: 99%

Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome

Błochowiak¹,

Olewicz‐Gawlik²,

Polańska³

et al. 2016

pdia

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“…Derived from Streptomyces nodosus cultures, microorganisms found in soil (Giannini and Shetty 2011 ;Vazquez 2010 ;Pappas et al 2009 ;Klotz 2006 ;Sharon and Fazel 2010 ;Thompson et al 2010 ;Neville et al 2002 ). Gold and colleagues discovered this macrolide in 1956.…”

Section: Amphotericin Bmentioning

confidence: 96%

“…It was the fi rst drug used for the treatment of systemic candidosis orally (Giannini and Shetty 2011 ;Muzyka and Glick 1995 ;Vazquez 2010 ;Pappas et al 2009 ;Park and Kang 2011 ;Klotz 2006 ;Sharon and Fazel 2010 ;Thompson et al 2010 ;Neville et al 2002 ;Greenspan 1994 ;Van Roey et al 2004 ). Only in rare cases of resistance to other antifungals the prescription of ketoconazole is necessary.…”

Section: Ketoconazolementioning

confidence: 98%

Antifungals for Candidosis Treatment

et al. 2015

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The available treatments for oral candidosis have proved to be more effi cacious with the use of new and known antifungal drugs. The success of these is directly related to the correct diagnosis, identifi cation, and correction of etiological factors and the commitment of the patient. In the absence of some of these factors, the antifungal therapy results only in a brief relief from disease, triggering relapses. This chapter presents the main drugs used in the treatment of oral and oropharyngeal candidosis, their functioning in the human body, and their mechanism of action in the destruction of the pathogenic agent.

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“…4 In the oral cavity, C. albicans can be seen as, various forms, such as pseudomembranous candidiasis, chronic plaque-type and nodular candidiasis, erythematous candidiasis, denture stomatitis, angular cheilitis, median rhomboid glossitis, and oral candidiasis associated with human immunodeficiency virus infection. [5][6][7] Before starting antifungal medication, it is necessary to eliminate any predisposing factor. Local…”

Section: Introductionmentioning

confidence: 99%

Antifungal Activity of Xylitol against Candida albicans: An in vitro Study

Talattof

Azad

Zahed

et al. 2018

The Journal of Contemporary Dental Practice

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Aim:The most common fungal infection among human population is candidiasis, the etiology of which is mostly Candida albicans. As a result of a disrupted balance of the normal flora or a compromised immune system, Candida species can become pathogenic. Various in vitro surveys have shown that glucose intake is a promoter of C. albicans growth, whereas in vivo studies have found that xylitol can decrease the risk of candidiasis and angular cheilitis. Hence, we aimed to evaluate for the first time the inhibitory effects of xylitol on C. albicans by assessing its minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC). Materials and methods:The standard strain of C. albicans was acquired. The fungi were incubated in supplemented brain-heart infusion broth for 48 hours at 37°C. The MIC was measured according to the Clinical and Laboratory Standards Institute (CLSI) M100-S24 standard. Microdilution method was applied using 360-µL sterilized polystyrene flat-bottomed 96-well plates. The antimicrobial effects were examined by the microbroth dilution method according to the CLSI M100-S24 standard. Results:The MIC of xylitol for C. albicans was found to be 20 × 10 4 µg/mL. Furthermore, the concentration of 40 × 10 4 µg/mL with a decrease of 99.95% in the colony-forming units (CFUs) of the microorganism was found to be the MFC of xylitol for C. albicans. Clinical significance: By knowing the MIC and MFC of xylitol, this substance can be effectively used in products aimed to cure this fungal infection. Conclusion:

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Oral candidiasis and angular cheilitis

Cited by 90 publications

References 63 publications

Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome

Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome

Antifungals for Candidosis Treatment

Antifungal Activity of Xylitol against Candida albicans: An in vitro Study

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