Oral Cutaneous Sinus Tract, Vertical Root Fracture, and Bisphosphonate-related Osteonecrosis: A Case Report

Bisphosphonate-related osteonecrosis of the jaw: from the sine qua non condition of bone exposure to a non-exposed BRONJ entity

“…61 emphasize the importance of a rigorous screening of the patient presenting with BRONJ signs and symptoms. It is crucial to look for oral infection to reduce it by means of endodontic and periodontal therapies as well as by using antimicrobial drugs.…”

Cutaneous Sinus Tract from Mandibular Second Molar with C-shaped Canal System and Improper Former Root Canal Treatment: A Case Report

“…After irrigation with saline, the root canals were dried with paper points (Dentsply Maillefer) and medicated with a calcium hydroxide-based paste (Quimis, Mallinkrodt, St. Louis, MO, USA) in a mixture with 2% chlorhexidine digluconate (Vista Dental Products, Racine, WI, USA) 7) . A 25-mm (1-in) #4 Lentulo spiral RA (Dentsply Maillefer) was used to place the paste passively.…”

“…Moreover, as none of the treatments given would actually address the root cause of the problem, the danger of recurrence is high. On the other hand, surgical or non-surgical root canal treatment, root canal retreatment, and even tooth extraction have been shown to promote healing within a matter of weeks in such cases 7) .…”

Immune cell profile of dental pulp tissue treated with zoledronic acid

“…), and there are some case reports of BRONJ induced by pulp and periapical diseases (Katz , Wigler et al . ). The major risk factor for BRONJ is tooth extraction, but ZA infusion generates a paradox: ZA can elevate the risk of developing pulpitis, which requires endodontic treatment, which is a conservative approach in the prevention of BRONJ.…”

“…Caution is suggested during the endodontic treatment of patients prescribed bisphosphonates due to the risk of BRONJ (Moinzadeh et al 2013). Endodontic treatment elevates the risk of BRONJ 5.5-fold (Barasch et al 2011), and there are some case reports of BRONJ induced by pulp and periapical diseases (Katz 2005, Wigler et al 2013. The major risk factor for BRONJ is tooth extraction, but ZA infusion generates a paradox: ZA can elevate the risk of developing pulpitis, which requires endodontic treatment, which is a conservative approach in the prevention of BRONJ.…”