Oral involvement in sarcoidosis: report of 12 cases

Abstract

Although oral manifestations of sarcoidosis are unusual, physicians should be aware that this specific localization is frequently the first manifestation of the disease. Treatment modalities range from observation in asymptomatic patients to immunosuppressants for severe involvement.

Unusual Clinical Presentations in Early-Onset Childhood Sarcoidosis: A Co-Relation or Co-Incidence?

“…Similarly, oral involvement is also an uncommon presentation of sarcoidosis [2]. In fact, there is only a hand full of cases exhibiting sarcoidosis-associated tongue impairment [10]. In our case, we observed geographical tongue in childhood sarcoidosis, which has not been reported previously.…”

Cutaneous Sarcoidosis

“…95 Mucosal disease Oral involvement of sarcoidosis is rare and morphologically can simulate cutaneous diseases with the presence of papules; nodules; erythema, including strawberry gums; and ulcerations. [100][101][102][103] Any portion of the oral cavity can be affected, and this can be the presenting sign of systemic disease. 102 Within the oral cavity, the buccal mucosa, gingiva, lips, tongue, and floor of mouth were most commonly affected, followed Cutaneous Sarcoidosis by the palate and submandibular glands.…”

Sarcoidosis

“…10). 89,90 Anogenital sarcoidosis, although rare, may manifest with tender indurated papules and nodules, pruritic scaly plaques, or swelling. [91][92][93][94] Nail sarcoidosis Nail manifestations caused by sarcoidosis include subungual hyperkeratosis, pitting, clubbing, onychorrhexis, trachyonychia, splinter hemorrhages, paronychia, pterygium, onycholysis, nail plate thinning, dactylitis, longitudinal ridging, and nail bed discoloration.…”