Oral pharmacological treatments for chronic prostatitis/chronic pelvic pain syndrome: A systematic review and network meta-analysis of randomised controlled trials

Chronic prostatitis (chronic pelvic pain syndrome)

“…Some randomised controlled trials (RCTs) have indicated benefits of pharmacological treatment, but a recent systematic review of 25 RCTs comparing one or more oral pharmacological treatments for patients with CPPS found little evidence to support their efficacy 17. The lack of high quality evidence means clinicians must weigh the benefits of medications against harms and prescribe according to a patient’s specific symptoms 17…”

Network pharmacology and in vivo experiment-based strategy for investigating the mechanism of chronic prostatitis/chronic pelvic pain syndrome in QianLieJinDan tablets

“…The main clinical symptoms of CP/CPPS are pelvic pain and discomfort (including in pelvic areas such as the perineum, suprapubic area, inguinal area, testicles or penis), varying degrees of urination, and sexual dysfunction; in some patients, there is even a tendency toward anxiety and depression, which seriously affects quality of life and physical and psychological well-being [ 1 , 2 ]. Epidemiologic surveys have shown that the symptomatic prevalence of CP/CPPS in China is 8.4 % [ 3 ]. Moreover, a study across several countries, including North America, Finland, and Singapore, has shown that the prevalence of CP/CPPS in men is 2%–10 % [ 2 ].…”

“…Moreover, a study across several countries, including North America, Finland, and Singapore, has shown that the prevalence of CP/CPPS in men is 2%–10 % [ 2 ]. A study showed that, due to the increase in life pressure and the influence of living habits, the CP/CPPS patient population tends to become younger, with 78.2 % of patients under the age of 40, exhibiting recurring pathological characteristics, and the prevalence of CP/CPPS increasing with age [ 3 , 4 ]. At present, analgesics, antibiotics, α-blockers and plant preparations are widely used to treat CP/CPPS.…”

Effects of nonpharmacological interventions on symptom clusters in breast cancer survivors: A systematic review of randomized controlled trials

“…An increasing number of randomized controlled trials (RCTs) have found that nonpharmacological interventions could improve cancer survivors' symptom management, reduce the use of medications, and have fewer side effects. 27 , 28 …”