Oral ulcers and cobblestone plaques. Oral Crohn's disease (CD)

Js, Weiss; Ak, Gupta; Regezi, Joseph A.; Je, Rasmussen

doi:10.1001/archderm.127.6.889

Cited by 5 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This may be attributed to the small numbers. Previous studies demonstrated an increased prevalence of various oral symptoms in patients with IBD (Schiller et al, 1971;Valery, 1972;O'Loughlin and Perry, 1978;Basu and Asquith, 1980;Rooney, 1984;Sundh and Hulten, 1984;Frankel and Mostofi, 1985;Sundh and Emilson, 1989;Alstead et al, 1991;Chan et al, 1991;Weiss et al, 1991;Philpot et al, 1992;Seo et al, 1992;Storwick et al, 1994;Calobrisi et al, 1995;Lisciandrano et al, 1996). A direct correlation between disease activity and the prevalence of other oral lesions was found by most (Basu et al, 1975;Basu and Asquith, 1980;Halme et al, 1993;Veloso et al, 1996) but not all (Lisciandrano et al, 1996) previous studies, and was attributed to an altered immune response after an exacerbation of CD.…”

Section: Discussionmentioning

confidence: 95%

“…Some authors cite diffuse or nodular swellings of the oral and perioral tissues as the most prominent features (Neville et al , 2002). Patients with CD may suffer from oral mucosal lesions such as aphthoid ulcerations, granulomatous and autoimmune‐like changes in minor salivary glands, reduced salivation, halitosis, dental erosion, pyostomatitis vegetans, angular cheilitis, candidiasis, odynophagia, dysphagia (Schiller et al , 1971; Valery, 1972; Basu and Asquith, 1980; Frankel and Mostofi, 1985; Schnitt et al , 1987; Weiss et al , 1991; Halme et al , 1993; Calobrisi, Mutasim and McDonald, 1995; Lisciandrano et al , 1996) and a high prevalence of caries (Rooney, 1984; Sundh and Hulten, 1984; Sundh and Emilson, 1989). Oral lesions found in patients with ulcerative colitis (UC) may include mucosal ulcers (Seo et al , 1992), pyostomatitis vegetans (Alstead, Wilson and Farthing, 1991; Chan, Scully and Prime, 1991; Philpot et al , 1992; Storwick et al , 1994; Calobrisi et al , 1995), diffuse pustules (O'Loughlin and Perry, 1978) and lichen planus (Davies and Shadforth, 1984; Alstead et al , 1991).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Oral signs and symptoms in relation to disease activity and site of involvement in patients with inflammatory bowel disease

et al. 2003

View full text Add to dashboard Cite

The present study demonstrates increased frequency of oral signs and symptoms in patients with IBD. Patients with active CD had more oral signs compared with non-active CD patients. Manifestations such as nausea, vomiting, regurgitation and dry mouth may have detrimental effects on teeth and soft tissues of the oral cavity. Communication between gastroenterologists and dentists is imperative for success of the overall treatment of their patients.

show abstract

Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Oral signs and symptoms in relation to disease activity and site of involvement in patients with inflammatory bowel disease

et al. 2003

View full text Add to dashboard Cite

show abstract

“…The phenomenon of oral ulcers and cobblestoning appearance in the mouth of patients with CD has been nicely illustrated in a significant number of cases. [51][52][53][54][55][56][57] Some authors are referring to them as 'CD of the mouth'. 58 The typical linear fissures and ulcerations have the same histopathological features of intestinal CD 59 (Figure 3).…”

Section: Spectrum Of Oral Manifestations In Ibdmentioning

confidence: 99%

“…The phenomenon of oral ulcers and cobblestoning appearance in the mouth of patients with CD has been nicely illustrated in a significant number of cases . Some authors are referring to them as ‘CD of the mouth’ .…”

Section: Spectrum Of Oral Manifestations In Ibdmentioning

confidence: 99%

Review article: non‐malignant oral manifestations in inflammatory bowel diseases

Κατσάνος

Torres

Roda

et al. 2015

Aliment Pharmacol Ther

View full text Add to dashboard Cite

Summary Background Patients with inflammatory bowel diseases (IBD) may present with lesions in their oral cavity. Lesions may be associated with the disease itself representing an extraintestinal manifestation, with nutritional deficiencies or with complications from therapy. Aim To review and describe the spectrum of oral nonmalignant manifestations in patients with inflammatory bowel diseases [ulcerative colitis (UC), Crohn's disease (CD)] and to critically review all relevant data. Methods A literature search using the terms and variants of all nonmalignant oral manifestations of inflammatory bowel diseases (UC, CD) was performed in November 2014 within Pubmed, Embase and Scopus and restricted to human studies. Results Oral lesions in IBD can be divided into three categories: (i) lesions highly specific for IBD, (ii) lesions highly suspicious of IBD and (iii) nonspecific lesions. Oral lesions are more common in CD compared to UC, and more prevalent in children. In adult CD patients, the prevalence rate of oral lesions is higher in CD patients with proximal gastrointestinal tract and/or perianal involvement, and estimated to range between 20% and 50%. Oral lesions can also occur in UC, with aphthous ulcers being the most frequent type. Oral manifestations in paediatric UC may be present in up to one‐third of patients and are usually nonspecific. Conclusions Oral manifestations in IBD can be a diagnostic challenge. Treatment generally involves managing the underlying intestinal disease. In cases presenting with local disabling symptoms and impaired quality of life, local and systemic medical therapy must be considered and/or oral surgery may be required.

show abstract

“…Oral ulcers, a cobblestone appearance of the oral mucosa and coexisting edema of the lips are well-documented symptoms of orofacial Crohn's disease (Fig. 2) [26][27][28]. Aphthous lesions are typically located on the labial and buccal mucosa but may also affect the tongue and oropharynx.…”

Section: Inflammatory Bowel Diseasesmentioning

confidence: 99%

Recurrent Aphthous Stomatitis – a Reflection of Gastrointestinal Diseases?

Lewkowicz¹

2015

Dent. Med. Probl.

View full text Add to dashboard Cite

Oral ulcers and cobblestone plaques. Oral Crohn's disease (CD)

Cited by 5 publications

References 0 publications

Oral signs and symptoms in relation to disease activity and site of involvement in patients with inflammatory bowel disease

Oral signs and symptoms in relation to disease activity and site of involvement in patients with inflammatory bowel disease

Review article: non‐malignant oral manifestations in inflammatory bowel diseases

Recurrent Aphthous Stomatitis – a Reflection of Gastrointestinal Diseases?

Contact Info

Product

Resources

About