Orale Kontrastmittel für die magnetische Resonanztomographie des Abdomens. Teil III: Erste Patientenuntersuchungen mit Gadolinium-DTPA

Claussen, C. D.; Kornmesser, W; Laniado, Michael; Kaminsky, S; Hamm, B.; Félix, R.

doi:10.1055/s-2008-1048272

Cited by 15 publications

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“…The results of this study therefore are not in accordance with previous studies [7,10,11,12,13,14] which report improvement in the diagnosis of abdominal malignant disease using MR imaging after oral administration of contrast agents.…”

Section: Discussioncontrasting

confidence: 76%

Local recurrence of rectal cancer: MR imaging before and after oral superparamagnetic particles vs contrast-enhanced computed tomography

et al. 2000

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The aim of this study was to compare three imaging strategies for the diagnosis of local recurrence of rectal cancer: (a) MR imaging; (b) MR imaging after administration of enteral superparamagnetic particles (Ferristene); and (c) contrast-enhanced CT. Seventeen patients with previous surgery for rectal cancer were examined, 12 patients with local tumour recurrence in the pelvis and 5 patients with postoperative changes. Pelvic multi-coil MR imaging before and after oral administration of superparamagnetic contrast medium [Abdoscan (Ferristene USAN), Nycomed-Amersham, Lidingö, Sweden] as well as abdominal and pelvic CT was performed in all patients. The examinations were independently evaluated by three different radiologists. The general effect of the oral MR contrast medium, the delineation of normal and pathological structures as well as confidence in the diagnosis were registered on a visual analog scale (VAS). The diagnosis according to MR before and after oral contrast medium, and CT, was compared, in 16 patients, with the final diagnosis which was verified by biopsy (n = 3), surgery (n = 6), clinical follow-up (n = 4) and by follow-up with MR or CT (n = 3). No significant improvement in MR image quality was found after enteral contrast medium. The post-contrast MR diagnosis was not changed in any of the patients. The diagnosis on MR correlated with the final diagnosis in 12 of 16 patients (sensitivity 91%, accuracy 62%) and the diagnosis on CT in 11 of 16 patients (sensitivity 82 %, accuracy 56 %). The radiologists' "confidence" in the diagnosis and the degree of accordance with the final diagnosis did not score higher on MR after than before oral contrast administration; however, the accordance with the final diagnosis scored better on MR than on CT. No advantages of orally administered superparamagnetic contrast medium were observed in the examined patient group. Magnetic resonance is preferable to CT in diagnosing local tumour recurrence.

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Section: Discussioncontrasting

confidence: 76%

Local recurrence of rectal cancer: MR imaging before and after oral superparamagnetic particles vs contrast-enhanced computed tomography

et al. 2000

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Abdominal imaging

Stark

Fahlvik²,

Klaveness³

1993

Magnetic Resonance Imaging

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Role of magnetic resonance imaging in the staging of gastrointestinal neoplasms

Ferraris

A²,

Galli³

2001

Seminars in Surgical Oncology

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A concise review is presented of the current applications and techniques of magnetic resonance imaging (MRI) in the field of diagnostic imaging of oncologic disease of the gastrointestinal tract, with a summary of the diagnostic possibilities of MRI in the various types of tumor pathology of the gastrointestinal tract. We conclude with a review of the specific situations in which MRI presents distinct advantages over other diagnostic imaging methods (such as computed tomography and ultrasound).

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Orale Kontrastmittel für die magnetische Resonanztomographie des Abdomens. Teil III: Erste Patientenuntersuchungen mit Gadolinium-DTPA

Cited by 15 publications

References 0 publications

Local recurrence of rectal cancer: MR imaging before and after oral superparamagnetic particles vs contrast-enhanced computed tomography

Local recurrence of rectal cancer: MR imaging before and after oral superparamagnetic particles vs contrast-enhanced computed tomography

Abdominal imaging

Role of magnetic resonance imaging in the staging of gastrointestinal neoplasms

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