“…Significant assault including but not limited to hemorrhage, abscess, tumor, orbital edema, or emphysema, or orbital cellulitis can lead to rapid rise in IOP >30 mmHg leading to ischemia and eventually irreversible vision loss [ 3 , 7 , 8 ]. Retinal ischemia for more than 90-120 minutes’ leads to high risk for permanent blindness and therefore, must be addressed immediately without any delay due to imaging [ 6 , 8 ]. Diagnosis of orbital compartment syndrome (OCS) is clinical and typically presents with the following: proptosis, ophthalmoplegia, relative afferent pupillary defect (RAPD), tense globe, tight eyelids in partially retracted position, elevated IOP, papilledema, optic atrophy, cherry red macula, venous congestion, or central retinal artery pulsation on fundoscopy [ 3 , 7 , 9 - 10 ].…”