Organ Donation in Three Major American Cities With Large Latino and Black Populations

Pérez, Luis Miguel Luengo; Schulman, Barbara; Davis, Faye; Olson, Les; Tellis, Vivian A.; Matas, Arthur J.

doi:10.1097/00007890-198810000-00017

Cited by 80 publications

(43 citation statements)

References 0 publications

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“…First, families who express uncertain understanding of the potential donors' wishes are less likely to authorize donation (59). Second, African American families have consistently been found to be less willing to donate than Caucasian families (60)(61)(62)(63)(64). These racial differences, likely rooted in historical distrust in the healthcare system (65), are compounded by observations that caregivers and OPO representatives may have less detailed conversations when discussing organ donation with African American families (63).…”

Section: Are Any Family Characteristics Associated With the Probabilimentioning

confidence: 99%

Management of the Potential Organ Donor in the ICU

Kotloff

Blosser

Fulda

et al. 2015

Critical Care Medicine

280

150

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This document was developed through the collaborative efforts of the Society of Critical Care Medicine, the American College of Chest Physicians, and the Association of Organ Procurement Organizations. Under the auspices of these societies, a multidisciplinary, multi-institutional task force was convened, incorporating expertise in critical care medicine, organ donor management, and transplantation. Members of the task force were divided into 13 subcommittees, each focused on one of the following general or organ-specific areas: death determination using neurologic criteria, donation after circulatory death determination, authorization process, general contraindications to donation, hemodynamic management, endocrine dysfunction and hormone replacement therapy, pediatric donor management, cardiac donation, lung donation, liver donation, kidney donation, small bowel donation, and pancreas donation. Subcommittees were charged with generating a series of management-related questions related to their topic. For each question, subcommittees provided a summary of relevant literature and specific recommendations. The specific recommendations were approved by all members of the task force and then assembled into a complete document. Because the available literature was overwhelmingly comprised of observational studies and case series, representing low-quality evidence, a decision was made that the document would assume the form of a consensus statement rather than a formally graded guideline. The goal of this document is to provide critical care practitioners with essential information and practical recommendations related to management of the potential organ donor, based on the available literature and expert consensus.

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Section: Are Any Family Characteristics Associated With the Probabilimentioning

confidence: 99%

Management of the Potential Organ Donor in the ICU

Kotloff

Blosser

Fulda

et al. 2015

Critical Care Medicine

280

150

View full text Add to dashboard Cite

show abstract

“…Many studies have shown that zero-HLA antigen-mismatched transplants have the highest success rates, and these findings have led to the allocation policy of mandatory sharing of zero-mismatched cadaver kidneys. Although only 9% of all cadaver kidney transplants in the United Network for Organ Sharing (UNOS) are zero-antigen mismatches (1), an organ allocation based on HLA matching is disadvantageous for racial minority groups who have different HLA antigen frequencies than the donor pool (2)(3)(4)(5).…”

mentioning

confidence: 99%

“…Nevertheless, small proportions of cadaver kidney transplants are matched at this level (1). During recent years, the concept of HLA matching within cross-reacting groups (CREG) of HLA-A and HLA-B antigens has been applied to increase the allocation of suitably matched kidneys (2)(3)(4)(5)(6)(7). Many studies have shown, however, that CREG-matched kidneys have lower graft survivals than the zero-antigen mismatches (8 -12).…”

mentioning

confidence: 99%

HLAmatchmaker: a molecularly based algorithm for histocompatibility determination. III. Effect of matching at the HLA-A,B amino acid triplet level on kidney transplant survival1

Duquesnoy

Takemoto²,

Lange³

et al. 2003

Transplantation

118

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“…It should also be taken into account that the population under analysis is heterogeneous, and there are important differences according to nationalities. 22,23 The Latin American population residing in Spain is relatively young. This could mean that attitudes and knowledge on the concept of brain death in their countries of origin are probably lower because usually older people are even less aware of these matters.…”

Section: Antonio Ríos Et Al/experimental and Clinical Transplantationmentioning

confidence: 99%

Untitled

Rı́os¹,

López-Navas²,

Martı́nez-Alarcón³

et al. 2018

Exp Clin Transplant

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Objectives: The knowledge of brain death is fundamental for being able to understand the organ donation process and for ensuring its acceptance or rejection. Here, we analyzed the level of knowledge of the concept of brain death among Latin-American individuals who are residents of Spain to determine the factors affecting this knowledge. Materials and Methods: Our patient group was a sample of 1314 Latin-American residents of Spain, obtained randomly and stratified according to the respondent's nationality, age, and sex. Their attitude was assessed using a validated questionnaire. The survey was self-administered and completed anonymously. Results: The questionnaire completion rate was 94% (n = 1237). Of total respondents, 25% (n = 313) knew the concept of brain death, which they considered to be an individual's death, 56% (n = 697) did not know the term, and 19% (n = 227) believed that it did not mean death. The variables related to knowledge of the brain death concept included (1) country of origin, with a better knowledge among those with Mexican nationality (P < .001); (2) male sex (30% vs 23%; P = .003); (3) having university-level education (35% vs 23%; P = .044); (4) having discussed the matter within the family (29% vs 23%; P = .044); (5) having a partner with a favorable attitude toward donation (39% vs 21%; P = .001); and (6) the respondent's religion (47% vs 7%; P < .001). The following factors persisted in the multivariate analysis: country of origin (odds ratio of 2.972), sex (odds ratio of 1.416), education level (odds ratio of 2.228), attitude of the respondent's partner (odds ratio of 1.835), and religion (odds ratio of 4.490). Conclusions: Knowledge of the concept of brain death is limited among Latin-American residents of Spain, with marked differences among country of origin and other socio-personal factors.

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Organ Donation in Three Major American Cities With Large Latino and Black Populations

Cited by 80 publications

References 0 publications

Management of the Potential Organ Donor in the ICU

Management of the Potential Organ Donor in the ICU

HLAmatchmaker: a molecularly based algorithm for histocompatibility determination. III. Effect of matching at the HLA-A,B amino acid triplet level on kidney transplant survival1

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