Bearberry [Arctostaphyllos uva-ursi (L.) Spreng., Ericaceae] is an official medicinal plant used in medical practice to treat a broad spectrum of diseases of the urogenital tract [1]. The active compounds of A. uva-ursi are phenolic glycosides, tannins, and flavonoids [2]; other classes of compounds are insufficiently studied. Considering the fact that the forms of A. uva-ursi used most often are aqueous extracts (decoctions, tinctures, and dry extracts obtained from aqueous extraction), we analyzed water-soluble polysaccharide components and pectinic substances in addition to hemicellulose of this type of plant raw material.Water-soluble polysaccharides (WSPS) were isolated from ground leaves of A. uva-ursi (200 g) by successive extraction in a Soxhlet apparatus using CHCl 3 , EtOAc, and (CH 3 ) 2 CO, after which the raw material was worked up exhaustively with water at 20 and 100°C. The extracts obtained at the different temperatures were concentrated separately and dialyzed through a cellulose-acetate membrane (Filtrak) against distilled water. The undialyzed remainder was precipitated by acetone (1:5). The resulting precipitates were centrifuged, demineralized by cation-exchanger KU-2-8 (H + -form), and deproteinized using pronase from Streptomyces griseus (Sigma) [3] to produce two fractions of water-soluble polysaccharides, WSPSc and WSPSh in yields of 0.708 and 0.512 g.WSPSc was a heterogeneous fraction that contained at least three components according to gel chromatography. The reaction with iodine was negative. The IR spectrum exhibited strong absorption bands for an α-bond (762.7 and 852.