In the chapter, topical issues of development of the competence-based bilingual educational programs for training of specialists of an engineering profile, capable to solve at the international level complex scientific and technical challenges taking into account requirements of professional standards are considered. The special attention is paid to methodology of synthesis of training systems including virtual laboratories, computer simulators, and systems of imitating modeling for the practical-oriented training of specialists. The method of estimates of acquired professional competences on the basis of models of control of knowledge is offered, to implementation of scenarios and the analysis of protocols of training that allows to increase safety and efficiency of productions due to growth of qualification of personnel of industrial enterprises.