The article attempts to define the concept of legal regulation of relations in the area of genetic technologies. The different models of legal regulation are used as a basis. Priority is given by the authors to the two-level model of legislation. This model consists of one Federal framework law, the provisions of which are supplemented by a group of special legislative acts which regulate certain aspects of genetic technologies. The authors present arguments in favor of choosing this model, in order to build a legislative system for genetic technologies and they highlight its advantages. The article concludes with a proposal to amend the current Federal Law of 5 July, 1996 No. 86-FZ ‘On State Regulation in the Field of Genetic Engineering’ which may serve as a basis for the development of the two-level model of legislation.