Organocatalytic aminocarbonylation of α,β-unsaturated ketones with N,N-dimethyl carbamoylsilane

Abstract

An organic superbase-catalyzed aminocarbonylation reaction of α,β-unsaturated ketones was reported. Under the catalysis of 10 mol% Schwesinger’s superbase t-Bu-P4, a variety of enones and ynone reacted with N, N-dimethyl carbamoylsilane...