Organogel composed of poloxamer 188 and passion fruit oil: Sol-gel transition, rheology, and mechanical properties

Francisco, Lizziane Maria Belloto de; Rosseto, Hélen Cássia; Toledo, Lucas de Alcântara Sica de; Santos, Rafaela Said dos; Ferreira, Sabrina Barbosa de Souza; Bruschi, Marcos Luciano

doi:10.1016/j.molliq.2019.111170

Cited by 22 publications

(23 citation statements)

References 31 publications

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“…Two curves were obtained in flow mode over shear rates ranging from 0 to 2000 s -1 and 2000 to 0 s -1 . The up curve was measured over 150 s, kept at the high limit for 10 s and, then decreased over 150 s (Barbosa et al, 2017;Bassi da Silva et al, 2017;de Francisco et al, 2019). The up curve was fitted by Oswald-de-Waele equation as shown below Eq.…”

Section: Continuous Shear (Flow) Analysismentioning

confidence: 99%

“…The frequency sweep analysis was then conducted from 0.1 to 10.0 Hz (Barbosa et al, 2017;Bassi da Silva et al, 2017;de Francisco et al, 2019). The storage modulus (G'), the loss modulus (G"), dynamic viscosity (') and loss tangent (tan ) were obtained using the RheoWin 4.10.0000 (Haakes  ) software.…”

Section: Oscillatory Measurementsmentioning

confidence: 99%

“…G', G″, η' and tan δ were calculated using the RheoWin 4.10.0000 (Haakes  ) software. The temperature at which the elastic modulus (G') was halfway between the values for the solution and for the gel was defined as Tsol/gel, based on the significant increase of dynamic viscosity (η') with increasing temperature (Barbosa et al, 2017;Bassi da Silva et al, 2017;Bruschi et al, 2007;de Francisco et al, 2019).…”

Section: Measurement Of Solution-gel Transition Temperature (Tsol/gel)mentioning

confidence: 99%

“…Hardness (maximum force during the compression), compressibility (the work required to deform the formulation during the first pass of the probe), adhesiveness (work required to overcome the attractive forces between the surfaces of the probe/sample), elasticity (ability to stretch and return to its original size and shape), and cohesiveness (work necessary to become united the surface of the sample and the surface of the probe) were calculated from the force-time and force-distance graphs, as demonstrated in Fig. S3 ( Barbosa et al, 2017;Bassi da Silva et al, 2017;Bruschi et al, 2007;de Francisco et al, 2019).…”

Section: Texture Profile Analysis (Tpa)mentioning

confidence: 99%

“…Polymer blends provide a simple approach to combine the advantages of different polymers, for example adhesiveness and environmental responsiveness (Barbosa et al, 2017;Borghi-Pangoni et al, 2015;Bruschi et al, 2007;Jones et al, 2009;Liu, Lin, Li, & Liu, 2005). Thermoresponsive gelling systems have been widely studied over the years for drug delivery, mainly due to their ease of application, spreadability and retention at the application site (de Francisco et al, 2019;Ramírez Barragán et al, 2018). Moreover, where these thermoresponsive materials are composed of nanostructured micelles derived from amphiphilic block copolymers they may improve solubilization, stabilization and control of drug delivery (Jindal & Mehta, 2015).…”

Section: Introductionmentioning

confidence: 99%

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Thermoresponsive systems composed of poloxamer 407 and HPMC or NaCMC: mechanical, rheological and sol-gel transition analysis

Silva

Cook

Bruschi

2020

Carbohydrate Polymers

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Poloxamer 407 (polox407) is widely studied as thermogelling polymer, transitioning to a gel state when warmed. Polox407 has the limitation that it forms weak hydrogels, with rapid dissolution in excess solvent. This study reports the development of new binary polymeric systems composed of polox407 and hydroxypropyl methylcellulose (HPMC) or sodium carboxymethylcellulose (NaCMC) with an aim to improve the rheological and mechanical properties of the hydrogel. The interaction between polox407 and cellulose derivatives was studied, and their interaction with biological surfaces predicted. The carbohydrates affected the mechanical and rheological behavior of polox407 in different ways, dependent on polymer type, concentration, and temperature.Tsol/gel and rheological interaction parameters were useful to select the most suitable formulations for topical or local application, ensuring in situ gelation and the formation of a strong gel. Most of the binary systems exhibited plastic behavior, with thixotropic and viscoelastic properties. Appropriate formulations were identified for local application, such as 17.

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Section: Continuous Shear (Flow) Analysismentioning

confidence: 99%

Section: Oscillatory Measurementsmentioning

confidence: 99%

Section: Measurement Of Solution-gel Transition Temperature (Tsol/gel)mentioning

confidence: 99%

Section: Texture Profile Analysis (Tpa)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Thermoresponsive systems composed of poloxamer 407 and HPMC or NaCMC: mechanical, rheological and sol-gel transition analysis

Silva

Cook

Bruschi

2020

Carbohydrate Polymers

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The effect of poly(acrylic acid) on temperature‐dependent behaviors and structural evolution of poloxamer 407

Hirun

Tantishaiyakul

Sangfai

et al. 2021

Polymer International

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Understanding temperature‐dependent behaviors and structural evolution plays an essential role in the development of thermosensitive hydrogels. In this work, thermosensitive hydrogels composed of poly(acrylic acid) (PAA) and poloxamer 407 (PX) were investigated. The effect of PAA on the thermosensitive micellization, gelation and structural evolution of 20% PX (20PX) was studied by means of differential scanning calorimetry (DSC), rheology and small angle X‐ray scattering. In addition, the structural and amplitude‐dependent rheological characteristics of mixtures of 20PX and various concentrations of PAA (PAA/PX) gels at body temperature were also examined. The DSC thermograms of the PAA/PX mixtures revealed overlapping double endothermic peaks, reflecting the micellization of PX micelles with attached PAA and pure PX micelles. The formation of PX micelles with attached PAA increased when PAA concentration was increased. The intermicellar packing of PX micelles might be interfered by the attached PAA; the presence of PAA modulated the gelation temperature. All thermosensitive systems showed disorder‐to‐order structural evolution upon heating. Although the micelles in the plain 20PX gel arranged into a face‐centered cubic (FCC) geometry, a body‐centered cubic (BCC) phase emerged in the PAA/PX mixtures and became predominant with increasing PAA concentration. The presence of PAA chains tailored the ordered structure of the gels and favored the BCC arrangement.The rheological and ordered structural properties of the PAA/PX gels at body temperature can be modulated by varying the concentration of PAA. © 2021 Society of Chemical Industry

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Effect of propolis on fungi of human clinical interest

Barros

Corrêa

Veiga

et al. 2022

Bee Products and Their Applications in the Food and Pharmaceutical Industries

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Organogel composed of poloxamer 188 and passion fruit oil: Sol-gel transition, rheology, and mechanical properties

Cited by 22 publications

References 31 publications

Thermoresponsive systems composed of poloxamer 407 and HPMC or NaCMC: mechanical, rheological and sol-gel transition analysis

Thermoresponsive systems composed of poloxamer 407 and HPMC or NaCMC: mechanical, rheological and sol-gel transition analysis

The effect of poly(acrylic acid) on temperature‐dependent behaviors and structural evolution of poloxamer 407

Effect of propolis on fungi of human clinical interest

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