Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of the Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Bhusal, Suzit; Bhandari, Rupa; Dahal, Sujata; Niroula, Aliska; Basnet, Krity; Chaudhary, Ashlesha; Pant, Subash

doi:10.31729/jnma.7823

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Perhaps, the mortality is higher in our study due to the group of poisoning agents. In our group, the mortality in the pesticide poisoning group was 4.5%, lower than reported in some studies (8%) (30,31). However, our mortality was higher compared to one study in the USA (0.07%) (32).…”

Section: Discussioncontrasting

confidence: 77%

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Hurtado,

Quintero,

Rodríguez

et al. 2023

Preprint

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Background Acute poisonings are a global public health problem, which implies costs and disease burden for society. In Colombia, there is a significant underreporting of data on acute poisoning and data gaps on the toxicological profile of the population. This study aims to identify the epidemiology of acute poisoning in a highly complex hospital in southwestern Colombia. Methods A descriptive study with retrospective data collection was performed. The variables were expressed through the measure of central tendency and dispersion. Categorical variables were described in proportions. Results A total of 406 patients were included. The median age was 31 years (IQR: 23–48), 56.2% were male, and only 19.2% had a history of mental illness. Suicidal intent represented 58.8% of the cases, and the most frequent route of exposure was the oral route (81.6%). The most prevalent groups of substances were pesticides (34.2%) and medicines (32%). The most common etiological agent was organophosphates (16.5%). Cholinergic toxidrome was the most common. The average stay in the ICU was 4.5 days (± 4.8), and the mortality was 4.2%. Conclusions The principal causes of acute poisoning were drugs and pesticides, with a predominant etiology of organophosphates and depressants of the central nervous system. There was a significant predominance of young male patients with suicidal intent, low mental disorders, elevated unemployment rate, and similar mortality reported in other studies. This study improves the knowledge about acute poisoning in southwestern Colombian to carry out multicenter analytics studies.

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Section: Discussioncontrasting

confidence: 77%

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Hurtado,

Quintero,

Rodríguez

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Perhaps, the mortality is higher in our study due to the group of poisoning agents. In our group, the mortality in the pesticide poisoning group was 4.5%, lower than reported in some studies (8%) 26 , 27 . However, our mortality was higher compared to one study in the USA (0.07%) 28 .…”

Section: Discussioncontrasting

confidence: 75%

Principal causes of acute poisoning in an emergency service: experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Hurtado,

Quintero,

Rodríguez

et al. 2024

Sci Rep

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Acute poisonings are a global public health problem, which implies costs and disease burden for society. In Colombia, there is a significant underreporting of data on acute poisoning and data gaps on the toxicological profile of the population. This study aims to identify the epidemiology of acute poisoning in a high-complexity hospital in southwestern Colombia. A descriptive study with retrospective data collection was performed. The variables were expressed through the measure of central tendency and dispersion. Categorical variables were described in proportions. A total of 406 patients were included. The median age was 31 years (IQR 23–48), 56.2% were male, and only 19.2% had a history of mental illness. Suicidal intent represented 58.8% of the cases, and the most frequent route of exposure was the oral route (81.6%). The most prevalent groups of substances were pesticides (34.2%) and medicines (32%). The most common etiological agent was organophosphates (16.5%). Cholinergic toxidrome was the most common. The average stay in the ICU was 4.5 days (± 4.8), and the mortality was 4.2%. The principal causes of acute poisoning were drugs and pesticides, with a predominant etiology of organophosphates and depressants of the central nervous system. There was a significant predominance of young male patients with suicidal intent, low mental disorders, elevated unemployment rate, and similar mortality reported in other studies. This study improves the knowledge about acute poisoning in southwestern Colombian to carry out multicenter analytic studies.

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Influence of sequential blood purification therapy on myocardial injury and serum inflammatory cytokine levels in patients with organophosphate poisoning

Mao

2024

Am J Transl Res

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Organophosphorus Poisoning among Patients Admitted to the Intensive Care Unit of the Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Cited by 3 publications

References 8 publications

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Principal causes of acute poisoning in an emergency service: Experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Principal causes of acute poisoning in an emergency service: experience between 2014 and 2021 at a University Hospital in Southwestern Colombia

Influence of sequential blood purification therapy on myocardial injury and serum inflammatory cytokine levels in patients with organophosphate poisoning

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