Organosulfur Compounds as Potential Fungicides: The Preparation and Properties of Some Substituted Benzyl 2-Hydroxyethyl Oligosulfides

Ayodele, E.T.; Hudson, H. R.; Ojo, I. A. O.; Pianka, M.

doi:10.1080/10426500008043656

Cited by 11 publications

(9 citation statements)

References 8 publications

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“…sulfides and disulfides) exhibited much lower or no activity in the antimicrobial assays. Our study has confirmed the antifungal activity of benzyl 2-hydroxyethyl trisulfide (15) that was first reported by Szczepanski et al (1972) and subsequently corroborated by Ayodele et al (2000). All three trisulfides tested (14-16) were significantly more active than the corresponding monoand disulfides (8-13).…”

Section: Discussionsupporting

confidence: 93%

“…Benzyl sulfide (8), bis(2-hydroxyethyl) sulfide (10), benzyl disulfide (11) and benzyl trisulfide (14) were purchased from Aldrich. Benzyl 2-hydroxyethyl sulfide (9), benzyl 2-hydroxyethyl disulfide (12), bis(2-hydroxyethyl) disulfide (13), benzyl 2-hydroxyethyl trisulfide (15) and bis(2-hydroxyethyl) trisulfide (16) were obtained as described in the literature (Ayodele et al, 2000). Sodium benzylsulfonate (17) was synthesized according to a published method (Johnson and Ambler, 1914), and benzylsulfinic acid (18) was prepared by hydrolysis of benzylsulfinyl chloride.…”

Section: Introductionmentioning

confidence: 99%

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Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.

Kim

Kubec

Musah

2006

Journal of Ethnopharmacology

125

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.

Kim

Kubec

Musah

2006

Journal of Ethnopharmacology

125

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“…40 In the present study, the sulfonation of DHI and DHICA monomers may also increase the cellular viability due to the fungicidal effect presented by organosulfur compounds. 41 Other studies supporting this hypothesis show that surface-modified sulfur nanoparticles also expressed promising inhibitory effects on fungal growth. 42 Cellular adhesion tests show the ability of fibroblast cells to adhere to melanin thin films.…”

Section: Discussionmentioning

confidence: 89%

Biocompatibility investigations of synthetic melanin and melanin analogue for application in bioelectronics

Piacenti-Silva

Matos

Paulin

et al. 2016

Polymer International

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Biocompatibility tests were performed for melanin synthesized in water (W‐Mel) and dimethylsulfoxide (D‐Mel) aiming to evaluate its potential for bioelectronics application. In vitro biocompatibility of melanin was assessed using crystal violet assays with fibroblast cells (NIH3T3) cultured with W‐Mel and D‐Mel extracts in various dilutions. The results show that a high concentration of melanin kills the cells. However, after periods of 48 h incubation, cell viability is significantly favored after treatment with D‐Mel at low concentrations (1:16, 1:32 and 1:64), as opposed to treatment with W‐Mel extracts. Cellular adhesion tests show that fibroblast cells adhere to melanin thin films. These results show that D‐Mel may be an interesting material for application in bioelectronic devices targeted for implants. © 2016 Society of Chemical Industry

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“…These include sulfenyl, thiono, thiocarbonyl, acyl, sulfinyl, sulfonyl phosphinothioyl and diatazole groups [12][13][14][15][16][17][18]. The most widely used functional group for the derivatization of carbamates is the sulfenyl group [15,16,[19][20][21][22]. Several types of N-sulfenylated carbamates have shown higher fungicidal activity than their corresponding parent compounds [1].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and fungicidal activity of some sulphide derivatives of O-phenyl-N-substituted phenylcarbamates

Adelowo¹,

Ojo²,

Amuda³

2011

ABC

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Monosulphides of O-phenyl-N-substituted phenylcar- bamates were prepared by the reaction between O- phenyl-N-substituted phenylcarbamates and sulph- ur dichloride while the corresponding disulphides were prepared by the reaction between O-phenyl-N- substituted phenylcarbamates and sulphur monoch- loride. The synthesized compounds were characte-rized by elemental analysis, thin layer chromatogra-phy (TLC), Fourier-transform infrared, 1H and 13C nuclear magnetic resonance spectroscopic techniques. In vitro fungicidal assay of these sulphides against Fusarium oxysporum, Aspergillus niger, Aspergillus flavus and Rhizopus stolonifer showed that they were more fungicidal than their parent carbamates. The synthesized sulphides were more active towards As-pergillus niger and Aspergillus flavus. There was little or no variations in the fungicidal activities of the synthesized monosulphides and disulphides of O-phen- yl-N-substituted phenyl carbamates

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Organosulfur Compounds as Potential Fungicides: The Preparation and Properties of Some Substituted Benzyl 2-Hydroxyethyl Oligosulfides

Cited by 11 publications

References 8 publications

Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.

Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.

Biocompatibility investigations of synthetic melanin and melanin analogue for application in bioelectronics

Synthesis and fungicidal activity of some sulphide derivatives of O-phenyl-N-substituted phenylcarbamates

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