Orientation of Aplysia californien to distant food sources

Teyke, Thomas; Weiss, Klaudiusz R.; Kupfermann, Irving

doi:10.1007/bf00191416

Cited by 19 publications

(13 citation statements)

References 27 publications

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“…For example, firing of the CPR polysynaptically hyperpolarized cerebral Bn neurons (Fig. lD), which are involved in defensive head withdrawal (20). The hyperpolarization of the Bn neurons resulted in decreased firing of the Bn cells in response to strong tactile stimulation of the tentacles.…”

Section: Reports 8smentioning

confidence: 97%

An Identified Neuron (CPR) Evokes Neuronal Responses Reflecting Food Arousal in Aplysia

Teyke

Weiss

Kupfermann

1990

Science

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Feeding behavior of Aplysia is associated with an arousal state characterized by a constellation of maintained behaviors and by a potentiation or depression of responses to specific stimuli. A neuron (the cerebral-pedal regulator or CPR) that has widespread actions on various systems connected with feeding has been identified. CPR excites neurons that modulate or drive (i) body posture, (ii) biting, and (iii) cardiovascular behaviors. CPR also inhibits neurons concerned with defensive responses. Food stimuli, which elicit food arousal in the animal, produce prolonged excitation of the CPR. The results suggest that the CPR may evoke a central motive state representing the neuronal correlate of feeding motivation.

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Section: Reports 8smentioning

confidence: 97%

An Identified Neuron (CPR) Evokes Neuronal Responses Reflecting Food Arousal in Aplysia

Teyke

Weiss

Kupfermann

1990

Science

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“…The gastropod mollusks are very useful models for the study of the neuronal basis of such complex behaviors (Kandel 1979). The behaviors have been well studied for odor preference (Audesirk 1975;Chase 1977, 1980;Peschel et al 1996;Teyke 1995;Teyke et al 1992;Willows 1978;Yamada et al 1992) and taste preference (Chang and Gelperin 1980;Culligan and Gelperin 1983;Kemenes et al 1986;Kupfermann and Carew 1974). For taste preference, the learning behaviors that associate specific tastes and textures with inedibility have been well studied (Botzer et al 1998;Schwarz and Susswein 1986;Schwarz et al 1988;Susswein et al 1986).…”

Section: Introductionmentioning

confidence: 99%

Cerebral CBm1 Neuron Contributes to Synaptic Modulation Appearing During Rejection of Seaweed inAplysia kurodai

Narusuye

Nagahama

2002

Journal of Neurophysiology

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Narusuye, Kenji, and Tatsumi Nagahama. Cerebral CBM1 neuron contributes to synaptic modulation appearing during rejection of seaweed in Aplysia kurodai. J Neurophysiol 88: 2778J Neurophysiol 88: -2795J Neurophysiol 88: , 2002 10.1152/jn.00757.2001. The Japanese species Aplysia kurodai feeds well on Ulva but rejects Gelidium with distinctive rhythmic patterned movements of the jaws and radula. We have previously shown that the patterned jaw movements during the rejection of Gelidium might be caused by long-lasting suppression of the monosynaptic transmission from the multiaction MA neurons to the jaw-closing (JC) motor neurons in the buccal ganglia and that the modulation might be directly produced by some cerebral neurons. In the present paper, we have identified a pair of catecholaminergic neurons (CBM1) in bilateral cerebral M clusters. The CBM1, probably equivalent to CBI-1 in A. californica, simultaneously produced monosynaptic excitatory postsynaptic potentials (EPSPs) in the MA and JC neurons. Firing of the CBM1 reduced the size of the inhibitory postsynaptic currents (IPSCs) in the JC neuron, evoked by the MA spikes, for Ͼ100 s. Moreover, the application of dopamine mimicked the CBM1 modulatory effects and pretreatment with a D1 antagonist, SCH23390, blocked the modulatory effects induced by dopamine. It could also largely block the modulatory effects induced by the CBM1 firing. These results suggest that the CBM1 may directly modulate the synaptic transmission by releasing dopamine. Moreover, we explored the CBM1 spike activity induced by taste stimulation of the animal lips with seaweed extracts by the use of calcium imaging. The calciumsensitive dye, Calcium Green-1, was iontophoretically loaded into a cell body of the CBM1 using a microelectrode. Application of either Ulva or Gelidium extract to the lips increased the fluorescence intensity, but the Gelidium extract always induced a larger change in fluorescence compared with the Ulva extract, although the solution used induced the maximum spike responses of the CBM1 for each of the seaweed extracts. When the firing frequency of the CBM1 activity after taste stimulation was estimated, the Gelidium extract induced a spike activity of ϳ30 spikes/s while the Ulva extract induced an activity of ϳ20 spikes/s, consistent with the effective firing frequency (Ͼ25 spikes/s) for the synaptic modulation. These results suggest that the CBM1 may be one of the cerebral neurons contributing to the modulation of the basic feeding circuits for rejection induced by the taste of seaweeds such as Gelidium.

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“…Contact of the food with the lips (Teyke et al 1990(Teyke et al , 1992 triggers a consummatory phase, in which food is grasped and propelled into the gut by means of rhythmic movements of the radula and buccal muscles.…”

Section: Introductionmentioning

confidence: 99%

Characterization of buccal motor programs elicited by a cholinergic agonist applied to the cerebral ganglion of Aplysia californica

et al. 1996

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Applying the non-hydrolyzable cholinergic agonist carbachol (CCh) to the cerebral ganglion of Aplysia elicits sustained, regular bursts of activity in the buccal ganglia resembling those seen during biting. The threshold for bursting is approximately 10(-4) M. Bursting begins after a 2 to 5 min delay. The burst frequency increases over the first 5 bursts, reaching a plateau value of approximately 3 per minute. Bursting is maintained for over 10 min. Some of the effects of CCh may be attributed to its ability to depolarize and fire CBI-2, a command-like neuron in the cerebral ganglion that initiates biting. CBI-2 is also depolarized by ACh, and by stimulating peripheral sensory nerves. Excitation of CBI-2 caused by carbachol is partially blocked by the muscarinic antagonist atropine. We examined whether CCh-induced bursting is modified in ganglia taken from Aplysia that previously experienced treatments inhibiting feeding, such as satiation, head shock contingent or non-contingent with food, and training animals with an inedible food. No treatment consistently and repeatedly affected the latency, the peak burst period, the length of time that bursting was maintained, or the threshold CCh concentration for eliciting bursting. However, there was a decrease in the rate of the build-up of the buccal ganglion program in previously satiated animals.

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Orientation of Aplysia californien to distant food sources

Cited by 19 publications

References 27 publications

An Identified Neuron (CPR) Evokes Neuronal Responses Reflecting Food Arousal in Aplysia

An Identified Neuron (CPR) Evokes Neuronal Responses Reflecting Food Arousal in Aplysia

Cerebral CBm1 Neuron Contributes to Synaptic Modulation Appearing During Rejection of Seaweed inAplysia kurodai

Characterization of buccal motor programs elicited by a cholinergic agonist applied to the cerebral ganglion of Aplysia californica

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