2021
DOI: 10.1002/jbm.a.37322
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Oriented homo‐epitaxial crystallization of polylactic acid displaying a biomimetic structure and improved blood compatibility

Abstract: Epitaxial crystallization and solid hot-drawing technology were employed to fabricate oriented homo-epitaxial crystallization of polylactic acid (PLA) with nano-topography to enhance its blood compatibility and mechanical characteristics as blood-contacting medical devices. The process involved solid hot stretching the PLA plates. A PLA nutrient solution was then used to immerse the oriented plates to dissolve some of the PLA solutes, ensuring plate integrity. Consequently, the drawing process exponentially en… Show more

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Cited by 5 publications
(3 citation statements)
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“…S10, † after contact for 24 h, the supernatant of Ti-SPD-Cl displays a colorless and transparent appearance, with OD values akin to the negative control group, suggesting good blood compatibility. 51 These results demonstrate that Ti-SPD-Cl can promote cell adhesion and preserve cellular membrane homeostasis, indicating good biocompatibility. The osteogenic ability is crucial for the integration of implants with surrounding tissues.…”
Section: Biomaterials Science Papermentioning
confidence: 68%
“…S10, † after contact for 24 h, the supernatant of Ti-SPD-Cl displays a colorless and transparent appearance, with OD values akin to the negative control group, suggesting good blood compatibility. 51 These results demonstrate that Ti-SPD-Cl can promote cell adhesion and preserve cellular membrane homeostasis, indicating good biocompatibility. The osteogenic ability is crucial for the integration of implants with surrounding tissues.…”
Section: Biomaterials Science Papermentioning
confidence: 68%
“…PLA is widely used in the medical field, and numerous reports on its good biocompatibility can be found in the literature [ 56 , 57 , 58 ].…”
Section: Discussionmentioning
confidence: 99%
“…PLA is characterized by decomposition into water and carbon dioxide under composting conditions of high temperature, high humidity, and the presence of microorganisms [31,32]. PLA is widely used in medical practice, and its biocompatibility has been widely reported [33][34][35]. However, there have been few reports on the use of FFF or PLA in dentistry.…”
Section: Introductionmentioning
confidence: 99%