Origins of Neural Crest Cell Diversity

Selleck, Mark A. J.; Scherson, Talma; Bronner‐Fraser, Marianne

doi:10.1006/dbio.1993.1217

Cited by 98 publications

(42 citation statements)

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“…As these ectodermally derived cells migrate, they contribute extensively to the formation of mesenchymal structures in the head and neck. Cell labeling studies have demonstrated that neural crest cells arising from rhombomeres 1-3 (r1-3) of anterior hindbrain migrate into the first branchial arch and, thereafter, reside within the maxillary and mandibular prominences (Osumi-Yamashita et al, 1990;Serbedzija et al, 1992;Bronner-Fraser, 1993;Selleck et al, 1993;Lumsden and Krumlauf, 1996). The migration of these rhombencephalic crest cells is regulated by growth factor signaling pathways and their downstream transcription factors before the CNC cells become committed to several different tissue types such as bone, cartilage, tooth, and cranial nerve ganglia (Noden, 1983(Noden, , 1991Lumsden, 1988;Graham and Lumsden, 1993;Le Douarin et al, 1993;Echelard et al, 1994;Imai et al, 1996;Trainor and Krumlauf, 2000).…”

Section: Fate Determination Of Cranial Neural Crest Cellsmentioning

confidence: 99%

Recent advances in craniofacial morphogenesis

Chai

Maxson

2006

Developmental Dynamics

541

503

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Craniofacial malformations are involved in three fourths of all congenital birth defects in humans, affecting the development of head, face, or neck. Tremendous progress in the study of craniofacial development has been made that places this field at the forefront of biomedical research. A concerted effort among evolutionary and developmental biologists, human geneticists, and tissue engineers has revealed important information on the molecular mechanisms that are crucial for the patterning and formation of craniofacial structures. Here, we highlight recent advances in our understanding of evo-devo as it relates to craniofacial morphogenesis, fate determination of cranial neural crest cells, and specific signaling pathways in regulating tissue-tissue interactions during patterning of craniofacial apparatus and the morphogenesis of tooth, mandible, and palate. Together, these findings will be beneficial for the understanding, treatment, and prevention of human congenital malformations and establish the foundation for craniofacial tissue regeneration. Developmental Dynamics 235:2353-2375, 2006.

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Section: Fate Determination Of Cranial Neural Crest Cellsmentioning

confidence: 99%

Recent advances in craniofacial morphogenesis

Chai

Maxson

2006

Developmental Dynamics

541

503

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“…Following neurulation, neural crest cells are located at the dorsal neural tube, from which they migrate extensively in a rostrocaudal wave, forming distinct streams and differentiating into several distinct tissue types, including neurons, glia, cartilage, bone and melanocytes. (Bronner-Fraser and Fraser, 1988;Knecht and Bronner-Fraser, 2002;Nicole Le Douarin, 1999;Selleck et al, 1993).…”

Section: Introductionmentioning

confidence: 99%

Live Image Profiling of Neural Crest Lineages in Zebrafish Transgenic Lines

Kwak

Park

Jung

et al. 2013

Molecules and Cells

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“…Marking individual trunk neural crest cells with fluorescent vital dyes has shown that progeny of a single neural crest cell can include cells as diverse as adrenomedullary cells, Schwann cells, neurons and pigment cells (Bronner-Fraser and Fraser, 1988;Bronner-Fraser and Fraser, 1989;Selleck et al, 1993). The fate of individual progeny of the initially labeled cells depends to a large degree on the environment in which they come to reside after the completion of their migration.…”

Section: Introductionmentioning

confidence: 99%

Dissimilar regulation of cell differentiation in mesencephalic (cranial)and sacral (trunk) neural crest cells in vitro

et al. 2003

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During development neural crest cells give rise to a wide variety of specialized cell types in response to cytokines from surrounding tissues. Depending on the cranial-caudal level of their origin, different populations of neural crest cells exhibit differential competence to respond to these signals as exemplified by the unique ability of cranial neural crest to form skeletal cell types. We show that in addition to differences in whether they respond to particular signals, cranial neural crest cells differ dramatically from the trunk neural crest cells in how they respond to specific extracellular signals, such that under identical conditions the same signal induces dissimilar cell fate decisions in the two populations in vitro. Conversely, the same differentiated cell types are induced by different signals in the two populations. These in vitro differences in neural crest response are consistent with in vivo manipulations. We also provide evidence that these differences in responsiveness are modulated, at least in part, by differential expression of Hox genes within the neural crest.

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Origins of Neural Crest Cell Diversity

Cited by 98 publications

References 0 publications

Recent advances in craniofacial morphogenesis

Recent advances in craniofacial morphogenesis

Live Image Profiling of Neural Crest Lineages in Zebrafish Transgenic Lines

Dissimilar regulation of cell differentiation in mesencephalic (cranial)and sacral (trunk) neural crest cells in vitro

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