Oronasal Ventilation Partitioning in Adults and Children: Effect on Aerosol Deposition in Airways

Becquemin, M.M.; Bertholon, Jean-François; Bouchikhi, A.; Malarbet, J.L.; Roy, M.

doi:10.1093/oxfordjournals.rpd.a032588

Cited by 24 publications

(24 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As in previous studies (3,7,14,21,22,25,31), our laboratory has shown that the nasal contribution to breathing decreases with increasing exercise (Fig. 1).…”

Section: Discussionsupporting

confidence: 84%

“…The level of ventilation at which this switch from nasal to oronasal breathing occurs has been previously referred to as the "oronasal switching point" (21). A number of studies, however, have shown that oronasal breathing occurs at resting ventilation in some individuals (3,7,14). Characterizing the ventilation level and variability across individuals for the relative contribution of nasal to total breathing is critical to the construction of ventilation activity patterns for accurately constructing the airflow apportionment (nasal or mouth) at various ventilation rates associated with different activities.…”

mentioning

confidence: 99%

“…The level of exercise at which the oronasal switching point occurs and the relative contributions of oral vs. nasal breathing at rest and during exercise have been studied by a number of investigators (3,7,14,21,22,25,27,31). The physiological determinants of the relative contributions to nasal and oral breathing during exercise are still not well understood.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Nasal contribution to breathing with exercise: effect of race and gender

Bennett

Zeman²,

Jarabek³

2003

Journal of Applied Physiology

View full text Add to dashboard Cite

Because the nose acts as a filter to prevent penetration of toxic particles and gases to the lower respiratory tract, the route of breathing, oral vs. nasal, may be an important determinant of toxicant dose to the lungs. Using respiratory inductance plethysmography and a nasal mask fitted with flowmeter, we measured the nasal contribution to breathing at rest and during exercise (to 60% maximum workload) in healthy young adults (men/women = 11/11 and Caucasian/African-American = 11/11). We found that the nasal contribution to breathing is less during submaximal exercise in the Caucasians vs. African-Americans (e.g., at 60% maximum workload, mean nasal-to-total ventilation ratio = 0.40 ± 0.21 and 0.65 ± 0.24, respectively, P < 0.05). This difference is likely due to the African-Americans' ability to achieve higher maximal inspiratory flows through their nose than the Caucasians. Men also had a lesser nasal contribution to breathing during exercise compared with women. This is likely due to greater minute ventilations at any given percentage of maximum workload in men vs. women.

show abstract

“…As in previous studies (3,7,14,21,22,25,31), our laboratory has shown that the nasal contribution to breathing decreases with increasing exercise (Fig. 1).…”

Section: Discussionsupporting

confidence: 84%

mentioning

confidence: 99%

See 1 more Smart Citation

Nasal contribution to breathing with exercise: effect of race and gender

Bennett

Zeman²,

Jarabek³

2003

Journal of Applied Physiology

View full text Add to dashboard Cite

show abstract

“…Bennett et al (2008) reported that children (n ¼ 12; 6e10 years) have a greater oral contribution than adults (n ¼ 11; 18e27 years) at rest (68 vs 88% nasal, respectively) and during exercise (47 vs 59% nasal at 40% maximum workload, respectively). Becquemin et al (1999) have also reported children to have a greater fraction of oral breathing than adults at rest and during exercise. In a study of 37 subjects from 7 to 72 years of age, James et al (1997) reported that two subjects (5.4%) breathed purely through the mouth, but provided no other characteristics of these individuals.…”

Section: Route Of Breathingmentioning

confidence: 96%

Deposition of Particles

Brown¹

2015

Comparative Biology of the Normal Lung

View full text Add to dashboard Cite

“…models. One study indicated that older children (8 -16 years old) exhibited more oral breathing at rest than did adults, who had mainly nasal breathing (Becquemin et al, 1999). The effect of heart motion on airway dimensions and airflows, the deviation of tracheobronchial airways from smooth right circular cylinders, and the shapes of bifurcations at airway branching points are other potentially-important factors that are not usually modeled.…”

Section: Basic Considerationsmentioning

confidence: 99%

Methods for modeling particle deposition as a function of age

Phalen

Oldham

2001

Respiration Physiology

View full text Add to dashboard Cite

The purpose of this paper is to review the application of mathematical models of inhaled particle deposition to people of various ages. The basic considerations of aerosol physics, biological characteristics and model structure are presented along with limitations inherent in modern modeling techniques. Application of the models to children and senescent adults has been largely based on extrapolating anatomical and physiological data from young adults to match the changes observed during growth and aging. Sample results are included for total particle deposition and deposition in the bronchial and pulmonary regions. The models proposed provide particle deposition predictions that are consistent with the scant measurements available. The models discussed appear to be on firm theoretical grounds, but they are largely limited in application to simple aerosols and average individuals. Also, additional validation of the computational predictions is needed.

show abstract

Oronasal Ventilation Partitioning in Adults and Children: Effect on Aerosol Deposition in Airways

Cited by 24 publications

References 0 publications

Nasal contribution to breathing with exercise: effect of race and gender

Nasal contribution to breathing with exercise: effect of race and gender

Deposition of Particles

Methods for modeling particle deposition as a function of age

Contact Info

Product

Resources

About