Oral health-related quality of life (OHRQoL) refers to impacts of oral health on physical, psychological, functional and social aspects of individuals. Among specific measurement instruments to assess OHRQoL in adolescents, the C-OIDP (Child Oral Impact on Daily Performances) questionnaire has demonstrated validity, reliability and suitable psychometric properties. Our aim was to identify cross-sectional studies using the C-OIDP questionnaire to perform a qualitative synthesis and assessment of their methodology and results. A literature electronic search was carried out on the PubMed-Medline, Scopus, Web of Science (WoS), EMBASE, LILACS and SciELO databases, followed by a study selection process and quality assessment. OHRQoL perceived by adolescents is related to age, sex and sociodemographic factors. Eating is the most frequently affected dimension and toothache is the first cause of impact, showing a generally mild intensity and severity of impact. The impact on oral quality of life is greater in younger adolescents. Several factors such as previous caries experience, the DMFT (Decayed, Missed, Filled, Tooth) index, caries in primary teeth, canker sores, bleeding gums and malocclusion have been associated with a lower level of OHRQoL. More longitudinal studies are needed to clarify divergent results and complete our knowledge of oral impacts on quality of life.