Orthokeratinized odontogenic cyst: a systematic review

Abstract

Objectives: The aims of the review were to evaluate the principal clinical and conventional radiographic features of orthokeratinized odontogenic cyst (OOC) by systematic review (SR), and to compare the frequency of OOC between four global groups. Methods: The databases searched were the PubMed interface of MEDLINE and LILACS. Only those reports of OOCs that occurred in a consecutive series of OOCs in the reporting authors' caseload were considered. Results: 37 reports on 36 case series were included in the SR. OOC affected males twice as frequently and the mandible almost 2.5 times as frequently. Although the mean age at first presentation was 35 years, the largest proportion of cases first presented in the third decade for the Western, East Asian and Latin American global groups. Seven reports included details of at least one clinical finding. 11 reported case series included at least 1 radiological feature. All OOCs were radiolucent, 93% were unilocular and 68% were associated with unerupted teeth. 28% of the reported case series included follow up. 4% of OCC recurred and all of these were in the Western global group. Conclusions: Although one feature of OOCs is that they are unlikely to recur, some do. Not only is there a lack of long-term follow up of large series with long-term outcomes of OOC, but there is a paucity of clinical and radiological details of OOC at initial presentation.

Multiple Orthokeratinized Odontogenic Cysts: A Case Report

“…It occurs in the jaw bones and about 1/2 to 2/3 of the cases have been reported to be associated with an impacted tooth [3,8], or have presented clinically as dentigerous cysts [5]. Sporadic OOC has been recently reported to be associated with two supernumerary teeth [9].…”

Lesions of the jaws presenting as radiolucencies on cone-beam CT

“…43 Like the ameloblastoma, the lingual cortex of OOCs expands down past the otherwise unaffected lower border of the mandible. 44 Unlike KCOTs 21 and ameloblastoma, 37,38 OOCs have so far not exhibited root resorption. 43,44 What to do with the mixed parakeratoticeorthokeratotic lesions that are neither wholly KCOT nor wholly OOC?…”

“…This is now called the orthokeratinised odontogenic cyst (OOC). 43,44 Recently it was shown that the KCOT and OOC differ radiologically. 43 Although multiple OOCs 45 unaccompanied by features suggestive of NBCCS have been reported, it should be reiterated that there are cases of multiple KCOTs that are also not accompanied by NBCCS features, particularly in East Asians.…”

Long-term results after treatment of extensive odontogenic cysts of the jaws: a review

“…Complications can occur, such as infection, mandibular fracture, or encroachment upon the maxillary sinus or the nasal cavity. Possible signs are swelling with or without pain and loosening or displacement of teeth [8][9][10].…”

“…In this imaging modality, cysts of the jaws appear as sharply delineated radiolucencies. In the case of infection, the margin can appear blurred [7,8]. Modern techniques, such as computed tomography (CT), magnetic resonance imaging (MRI), or cone beam CT, can sometimes yield additional information about the cyst's size and relationship to endangered structures.…”