Orthopedics

Auth, Patrick

doi:10.1016/b978-141604485-7.50028-7

Cited by 8 publications

(7 citation statements)

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“…The hip joint begins to develop physiologically from mesenchymal cells as early as the fifth or sixth gestational week. By the eleventh week, the femoral head is completely formed [8], and in the coming weeks it undergoes a more rapid growth than the acetabular cartilage, causing about 50% of the femoral cartilage to be present at the time of birth, but in the postnatal period, the cartilage begins to develop much faster. If laxity of the femoral head is present after birth, Neonatal Hip Instability (NHI) can be diagnosed.…”

Section: Etiopathogenesismentioning

confidence: 99%

Developmental Dysplasia of the Hip: A Review of Etiopathogenesis, Risk Factors, and Genetic Aspects

Harsanyi¹,

Zamborský²,

Krajčíová³

et al. 2020

Medicina

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As one of the most frequent skeletal anomalies, developmental dysplasia of the hip (DDH) is characterized by a considerable range of pathology, from minor laxity of ligaments in the hip joint to complete luxation. Multifactorial etiology, of which the candidate genes have been studied the most, poses a challenge in understanding this disorder. Candidate gene association studies (CGASs) along with genome-wide association studies (GWASs) and genome-wide linkage analyses (GWLAs) have found numerous genes and loci with susceptible DDH association. Studies put major importance on candidate genes associated with the formation of connective tissue (COL1A1), osteogenesis (PAPPA2, GDF5), chondrogenesis (UQCC1, ASPN) and cell growth, proliferation and differentiation (TGFB1). Recent studies show that epigenetic factors, such as DNA methylation affect gene expression and therefore could play an important role in DDH pathogenesis. This paper reviews all existing risk factors affecting DDH incidence, along with candidate genes associated with genetic or epigenetic etiology of DDH in various studies.

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Section: Etiopathogenesismentioning

confidence: 99%

Developmental Dysplasia of the Hip: A Review of Etiopathogenesis, Risk Factors, and Genetic Aspects

Harsanyi¹,

Zamborský²,

Krajčíová³

et al. 2020

Medicina

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“…Significant number of studies have been done in the past few years to understand of the mechanism of performance boost with embedded stressors and to optimize the device structure and process conditions. These include the effect of stressor volume and proximity to the channel, epitaxy overfill/underfill (10), epitaxy grading (11), recess shape (12), and the impact of the replacement gate process (13,14).…”

Section: Embedded Stressorsmentioning

confidence: 99%

(Invited) Strain Engineering for Fully-Depleted SOI Devices

Khakifirooz

Kulkarni²,

Bedell³

et al. 2010

ECS Trans.

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“…There may be a decreased ability to move the arm and the person may present holding there elbow. Complications may include injury to an artery or nerve, and compartment syndrome [1,2] . The cause of a humerus fracture is usually physical trauma such as a fall.…”

Section: Introductionmentioning

confidence: 99%

Surgical management of proximal humeral fractures by locking plates

Kumar¹

2019

Int. J. Orthop. Sci.

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A humerus fracture is a break of the humerus bone in the upper arm. Symptoms may include pain, swelling, and bruising. There may be a decreased ability to move the arm and the person may present holding there elbow. Complications may include injury to an artery or nerve, and compartment syndrome.Objective: To study the efficacy, functional outcome for union of the fracture following surgery with locking plates in proximal humeral fractures. The present study was carried out between June 2015 to May 2016 in Orthopedic Department, Vydehi institute of medical sciences and research centre. In the proposed study 30 cases presenting with proximal humeral fractures are evaluated clinically and radio logically. In the present study maximum number of patients belongs to 31 to 40 years age group (12 cases) followed by 41 to 50 years age group (8 cases), maximum number of patients sustained femur fracture due to RTA (22 cases) followed by fall (08 cases), maximum number of patients sustained two part fracture (17 cases), followed by three part fracture (09 cases), four part fracture was seen in 3 cases and fracture dislocation in 1 case, 10 patients had excellent functional results and 15 patients had good functional outcome, while only 4 patients had fair functional outcome. The majority of patients can be treated with a sling or brace, and with time the fracture will heal. Casting is not possible with most types of humerus fractures. Surgery may be required when the bone fragments are far out of position.

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Orthopedics

Cited by 8 publications

References 0 publications

Developmental Dysplasia of the Hip: A Review of Etiopathogenesis, Risk Factors, and Genetic Aspects

Developmental Dysplasia of the Hip: A Review of Etiopathogenesis, Risk Factors, and Genetic Aspects

(Invited) Strain Engineering for Fully-Depleted SOI Devices

Surgical management of proximal humeral fractures by locking plates

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