Ossifying fibroma: a systematic review

MacDonald-Jankowski, D S

doi:10.1259/dmfr/70933621

Cited by 102 publications

(106 citation statements)

References 66 publications

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“…This more aggressive variant is further subdivided into trabecular and psammomatoid juvenile OF -the first is associated with pediatric patients and usually involves the maxilla, while the second is associated with adolescents and adults and usually involves the orbit and paranasal sinuses [1][2][3]. True OF is relatively rare, since, for a long time, the lesions that were so diagnosed were in fact focal cemento-osseous dysplasias [1,2,4].…”

Section: Discussionmentioning

confidence: 99%

“…OF can occur at any age, but is more common in the third and fourth decades of life [1][2][3][4][5][6]11]. In a review of published cases, the mean age of patients with OF was 25-26 years [2].…”

Section: Discussionmentioning

confidence: 99%

“…In a review of published cases, the mean age of patients with OF was 25-26 years [2]. This tumor is more frequent in women [2][3][4][5]11], with a predilection for the mandible, where the most common site of involvement is the molar/premolar region [2][3][4][5][6]. Although most studies indicate a higher prevalence in women, there are data that appear to show the opposite, such as those of a recently published 10-year retrospective analysis, which reported a prevalence rate of 56% in men [12].…”

Section: Discussionmentioning

confidence: 99%

“…This benign fibroosseous tumor is most commonly found in the mandibular molar/premolar region and occurs predominantly in the third and fourth decades of life, affecting women more than men [1][2][3][4][5][6]. OF consists of intraosseous fibrous tissue that exhibits varying degrees of cellularity and contains mineralized material.…”

Section: Introductionmentioning

confidence: 99%

“…OF consists of intraosseous fibrous tissue that exhibits varying degrees of cellularity and contains mineralized material. It appears as a well-circumscribed lesion that may or may not be surrounded by a fibrous capsule [1,2,4].…”

Section: Introductionmentioning

confidence: 99%

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Ossifying fibroma – diagnosis, treatment, and follow-up: case report and literature review

Andriola

Zanettini

Barreiro

et al. 2017

Rev. Odonto Ciênc. (Online)

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OBJECTIVE: This article presents a case of ossifying fibroma (OF), including its diagnosis, treatment, and 15-month clinical and radiographic follow-up as well as a review of the literature about this pathology. CASE REPORT: A routine panoramic radiograph of a 27-year-old, systemically healthy, white woman revealed a radiolucent lesion with well-defined sclerotic margins of approximately 3 × 2 cm in the mandible. The histopathological diagnosis revealed it was an OF. Lower Right Canine and Lower Right First Premolar teeth were endodontically treated for later surgical removal of the tumor. There was no history of trauma in the region. CONCLUSION: OF is a benign fibro-osseous tumor of the craniofacial bones commonly involving the jaws, especially the mandible. The diagnosis is based on a combination of clinical, radiographic and histologic criteria. Conservative treatment is an effective option that reduces morbidity and simplifies postoperative rehabilitation. We emphasize the importance of properly documenting individual cases and interpreting postoperative radiographic images along with the patients in order to avoid possible confusion between areas of bone repair and of potentially suspicious lesions in the future.Key words: Surgery, Oral; Pathology, Oral; Fibroma, Ossifying Fibroma ossificante -diagnóstico, tratamento e acompanhamento: relato de caso e revisão da literatura RESUMO OBJETIVO: Este artigo apresenta um caso de fibroma ossificante (OF), incluindo seu diagnóstico, tratamento e acompanhamento clínico e radiográfico de 15 meses, bem como uma revisão da literatura sobre esta patologia. RELATO DO CASO: Uma radiografia panorâmica de rotina de uma mulher branca de 27 anos, sistemicamente saudável, revelou uma lesão radiolúcida com margens escleróticas bem definidas de aproximadamente 3 × 2 cm na mandíbula. O diagnóstico histopatológico revelou que era um FO. O Canino Inferior Direito e o Pré-Molar Inferior Direito foram tratados endodonticamente para posterior remoção cirúrgica do tumor. Não havia história de trauma na região. CONCLUSãO: O FO é um tumor fibro-ósseo benigno dos ossos craniofaciais que comumente envolve os ossos maxilares, especialmente a mandíbula. O diagnóstico é baseado em uma combinação de critérios clínicos, radiográficos e histológicos. O tratamento conservador é uma opção eficaz que reduz a morbidade e simplifica a reabilitação pós-operatória. Ressaltamos a importância de uma adequada documentação dos casos, bem como do esclarecimento sobre a evolução das imagens radiográficas pós-operatórias junto aos pacientes, de modo a evitar possíveis confusões entre as áreas de reparo ósseo e suspeitas de novas lesões no futuro.

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