Osteoblast-Related Gene Expression of Rat Bone Marrow Cells Induced by Three-dimensional Cell Culture in Type I Collagen Gel.

Autologous periodontal ligament cells in the treatment of class III furcation defects: a study in dogs

“…() and Miyamoto et al. () observed a greater expression of bone markers and an increase mineral nodule formation when bone marrow cells were cultured in collagen scaffold. This could help explain the observation of ankylosis in some areas where the sponges were applied.…”

Bone Perforation and Placement of Collagen Sponge Facilitate Bone Augmentation

“…Moreover, collagen may stimulate cell differentiation of connective tissue progenitor cells 26 and osteoblast‐caused calcification. Miyamoto et al 21 reported that the expression of osseous markers in the bone marrow cell, such as alkaline phosphatase, osteopontin, and BSP, might be enhanced in cell cultures with collagen gel. Therefore, significant bone augmentation in the PS group might have been due to the combined effect induced by the bone marrow cells, cytokines, and collagen sponge.…”

“…Therefore, type I collagen is widely used for tissue grafts 15,16 and as a regenerative scaffold 17–19 . Moreover, type I collagen stimulates osteoblastic differentiation of bone marrow cells and osteogenesis in vitro 20,21 …”

Embryological study of the development of the rat temporomandibular joint: highlighting the development of the glenoid fossa

“…[3][4][5][6][7] Molecular biological research on the development of the skeletal system, especially the long bones, has been advancing, and the molecular biological mechanism of the pathway from mesenchymal condensation to chondrocyte formation and, finally, to osteoblast formation, is gradually unraveling. [8][9][10][11][12][13] However, the research in this field regarding the mandible and temporomandibular joint is sporadic. A more complete understanding of not only the embryology of these structures but also of the mechanisms of the molecular biological pathways involved is needed.…”