1983
DOI: 10.1080/00150198308009062
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Osteogenesis induced by bimorph polyvinylidene fluoride films

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1985
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Cited by 14 publications
(10 citation statements)
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“…The ferroelectric property of PVDF or its copolymers gives the opportunity to actively influence the pool of biological cells placed on its surface. It has been demonstrated that an increase in the ferroelectric β phase stimulates the differentiation of mesenchymal stem cells (MSC) in osteoblasts [15,16] and accelerates the regeneration of bone tissue [17,18] and stimulates attachment of neurons [19,20]. Devices made using polymeric ferroelectric materials were previously used for mechanical stimulation of osteoblasts [21,22].…”
Section: Introductionmentioning
confidence: 99%
“…The ferroelectric property of PVDF or its copolymers gives the opportunity to actively influence the pool of biological cells placed on its surface. It has been demonstrated that an increase in the ferroelectric β phase stimulates the differentiation of mesenchymal stem cells (MSC) in osteoblasts [15,16] and accelerates the regeneration of bone tissue [17,18] and stimulates attachment of neurons [19,20]. Devices made using polymeric ferroelectric materials were previously used for mechanical stimulation of osteoblasts [21,22].…”
Section: Introductionmentioning
confidence: 99%
“…На основании полученных исследователями данных была выдвинута гипотеза, что при контакте с биологическими тканями электрет может своим полем оказывать дозированное локальное воздействие на электретные свойства тканей поврежденного органа, способствуя его репарации в оп-тимальных биофизических условиях. Это инициировало исследования, направленные на оценку влияния меди-цинских электретов на репарацию различных тканей организма [4, [10][11][12][13][14]. Наиболее активно рассматривается вопрос по влиянию отрицательно заряженных электре-тов на остеогенез и репаративную регенерацию костной ткани.…”
Section: Introductionunclassified
“…Fukada first proposed this idea (Fukada et al, 1975) and it was further developed by Ficat (1983). In this latter work, a thin film of a piezo-electric polymer was wrapped around an intact rabbit tibia and new bone formation was seen with the newly formed osteons aligned in relation to the electric field.…”
Section: Introductionmentioning
confidence: 99%