Osteopathic Manipulation Treatment Improves Cerebro–splanchnic Oximetry in Late Preterm Infants

Abstract

Background: To evaluate the effectiveness/side-effects of osteopathic manipulation treatment (OMT) performed on the 7th post-natal day, on cerebro–splanchnic oximetry, tissue activation and hemodynamic redistribution in late preterm (LP) infants by using near infrared spectroscopy (NIRS). Methods: Observational pretest-test study consisting in a cohort of 18 LPs who received OMT on the 7th post-natal day. NIRS monitoring was performed at three different time-points: 30 min before (T0), (30 min during (T1) and 30 min after OMT (T2). We evaluated the effects of OMT on the following NIRS parameters: cerebral (c), splanchnic (s) regional oximetry (rSO2), cerebro–splanchnic fractional tissue oxygen extraction (FTOE) and hemodynamic redistribution (CSOR). Results: crSO2 and cFTOE significantly (P < 0.001) improved at T0-T2; srSO2 significantly (P < 0.001) decreased and sFTOE increased at T0-T1. Furthermore, srSO2 and sFTOE significantly improved at T1-T2. Finally, CSOR significantly (P < 0.05) increased at T0-T2. Conclusions: The present data show that OMT enhances cerebro–splanchnic oximetry, tissue activation and hemodynamic redistribution in the absence of any adverse clinical or laboratory pattern. The results indicate the usefulness of further randomized studies in wider populations comparing the effectiveness of OMT with standard rehabilitation programs.

Advances in Near Infrared Spectroscopy and Related Computational Methods

“…However, for sake of clarity a tentative and brief overview of these contributions may be helpful to present the Special Issue to the readership. The majority of the articles focuses on applied qualitative and quantitative analyses in a variety of fields [9,11,12,[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34]. Roughly, half of these may be associated with pharmaceutical and medical applications [17][18][19][20][21][22][23][24].…”

“…The majority of the articles focuses on applied qualitative and quantitative analyses in a variety of fields [9,11,12,[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34]. Roughly, half of these may be associated with pharmaceutical and medical applications [17][18][19][20][21][22][23][24]. Most of the remaining applied studies were directed at agricultural applications [25][26][27][28][29][30][31][32][33][34], well reflecting the ever-growing significance of NIR spectroscopy in this area; a good perspective of this topic is included in a focused review article published in the Special Issue [30].…”

Advances in Near-Infrared Spectroscopy and Related Computational Methods

“…The Special Issue has met a remarkably positive feedback with many contributions submitted by numerous scholars and professional spectroscopists performing their active research in academia and industry, resulting in a collection of 30 publications including two exhaustive review articles [7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36]. The diversity in the application field has been well represented by the submitted manuscripts.…”

“…However, for sake of clarity a tentative and brief overview of these contributions may be helpful to present the Special Issue to the readership. The majority of the articles focuses on applied qualitative and quantitative analyses in a variety of fields [9,11,12,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34]. Roughly, half of these may be associated with pharmaceutical and medical applications [17,18,19,20,21,22,23,24].…”

“…The majority of the articles focuses on applied qualitative and quantitative analyses in a variety of fields [9,11,12,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34]. Roughly, half of these may be associated with pharmaceutical and medical applications [17,18,19,20,21,22,23,24]. Most of the remaining applied studies were directed at agricultural applications [25,26,27,28,29,30,31,32,33,34], well reflecting the ever-growing significance of NIR spectroscopy in this area; a good perspective of this topic is included in a focused review article published in the Special Issue [30].…”